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Generated: February 23, 2019

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CLINICAL TRIALS PROFILE FOR TRIAZOLAM

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Clinical Trials for Triazolam

Trial ID Title Status Sponsor Phase Summary
NCT00671632 Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse Completed Takeda Phase 2 The purpose of this study is to determine the relative abuse potential of ramelteon, once daily (QD), compared to triazolam in subjects with a history of drug abuse.
NCT00695630 Flumazenil Reversal of Oral Triazolam Completed National Institutes of Health (NIH) Phase 1/Phase 2 An increase in the utilization of anesthesia and sedation medications by non-anesthesiologists, including dentists, has grown dramatically. This has been prompted, in part, by the need for pharmacological tools to address high levels of fear and anxiety about dental care among the US population and the evidence of oral health disparities among those who are fearful . Given the prevalence of dental fear in the general population and in the various populations with the greatest burden of oral diseases, effective sedation techniques are needed that are safe and effective in the hands of general dentists that make up the "front line" in the efforts to reduce oral health disparities. This study is to determine whether, when compared to a saline placebo, a single intraoral submucosal administration of the benzodiazepine antagonist flumazenil (0.2 mg) is capable of attenuating in 10 minutes or less the central nervous system (CNS) depression produced by a paradigm of stacked sublingual dosing of triazolam (3 doses of 0.25 mg over 90 minutes).
NCT00695630 Flumazenil Reversal of Oral Triazolam Completed University of Washington Phase 1/Phase 2 An increase in the utilization of anesthesia and sedation medications by non-anesthesiologists, including dentists, has grown dramatically. This has been prompted, in part, by the need for pharmacological tools to address high levels of fear and anxiety about dental care among the US population and the evidence of oral health disparities among those who are fearful . Given the prevalence of dental fear in the general population and in the various populations with the greatest burden of oral diseases, effective sedation techniques are needed that are safe and effective in the hands of general dentists that make up the "front line" in the efforts to reduce oral health disparities. This study is to determine whether, when compared to a saline placebo, a single intraoral submucosal administration of the benzodiazepine antagonist flumazenil (0.2 mg) is capable of attenuating in 10 minutes or less the central nervous system (CNS) depression produced by a paradigm of stacked sublingual dosing of triazolam (3 doses of 0.25 mg over 90 minutes).
NCT00894699 A Study to Evaluate the Clinical Efficacy, Safety and Tolerability of ARX-F03 Sublingual Sufentanil/Triazolam NanoTab™ in Patients Undergoing an Elective Abdominal Liposuction Procedure Completed AcelRx Pharmaceuticals, Inc. Phase 2 The purpose of this study is to evaluate the safety and effectiveness of a study medication that contains a combination of a pain medication, sufentanil, and a sedative, triazolam. This drug is being designed to provide mild sedation as well as reduce anxiety and pain before and during a procedure (in this case elective abdominal liposuction).
NCT01017926 Triazolam Trial In Healthy Subjects To Compare Bioavailability Between Formulations Of Triazolam To Determine Their Bioequivalence In Terms Of Rate And Magnitude Of Absorption Withdrawn Investigación Farmacológica y Biofarmacéutica Phase 1 The purpose of this study is to compare the bioavailability of two oral formulations of Triazolam in healthy volunteers, in order to determine that they are bioequivalent.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Triazolam

Condition Name

Condition Name for Triazolam
Intervention Trials
Healthy 3
Sedation 2
Dental Anxiety 2
Healthy Volunteers 1
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Condition MeSH

Condition MeSH for Triazolam
Intervention Trials
Hepatitis C 1
Sleep Deprivation 1
Substance-Related Disorders 1
Psychotic Disorders 1
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Clinical Trial Locations for Triazolam

Trials by Country

Trials by Country for Triazolam
Location Trials
United States 8
Switzerland 1
United Kingdom 1
Belgium 1
Lebanon 1
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Trials by US State

Trials by US State for Triazolam
Location Trials
Massachusetts 1
Texas 1
Georgia 1
Florida 1
Missouri 1
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Clinical Trial Progress for Triazolam

Clinical Trial Phase

Clinical Trial Phase for Triazolam
Clinical Trial Phase Trials
Phase 4 3
Phase 3 2
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Triazolam
Clinical Trial Phase Trials
Completed 9
Not yet recruiting 2
Recruiting 1
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Clinical Trial Sponsors for Triazolam

Sponsor Name

Sponsor Name for Triazolam
Sponsor Trials
Pfizer 3
University of Pittsburgh 1
National Institutes of Health (NIH) 1
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Sponsor Type

Sponsor Type for Triazolam
Sponsor Trials
Other 20
Industry 6
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Cipla
AstraZeneca
Julphar
US Department of Justice
Fuji
Federal Trade Commission
Deloitte
Medtronic

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