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Last Updated: November 28, 2022

CLINICAL TRIALS PROFILE FOR TRENTAL


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All Clinical Trials for Trental

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000646 ↗ Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed Hoechst Marion Roussel Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
NCT00000646 ↗ Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
NCT00243789 ↗ Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy Completed Cooperative International Neuromuscular Research Group Phase 1/Phase 2 2005-09-01 The purpose of this study is to see if male children with Duchenne muscular dystrophy (DMD) have changes in strength when given the drug Pentoxifylline as a rescue treatment. A total of 64 subjects are expected to participate through all other centers of the Cooperative International Neuromuscular Research Group (CINRG) worldwide. The primary purpose of this study is to see whether the addition of pentoxifylline to a steroid regimen is effective in treating deteriorating muscle strength by comparing the muscle strength of PTX treated subjects and placebo treated subjects.
NCT00267670 ↗ Pentoxifylline/Nonalcoholic Steatohepatitis (NASH) Study: The Effect of Pentoxifylline on NASH Completed Northwestern University Phase 2/Phase 3 2005-03-01 The purpose of this study is to explore the potential benefit of the medication, pentoxifylline, for the treatment of NASH.
NCT00354198 ↗ Efficacy of Pentoxifylline on Rapidly Progressive Glomerulonephritis Terminated National Science Council, Taiwan Phase 3 2006-08-01 We have recently demonstrated that pentoxifylline (PTX) has the potential to treat severe glomerular inflammation in a rat model of accelerated anti-glomerular basement membrane (GBM) glomerulonephritis. This study aims to investigate the therapeutic effects of combined PTX and conventional immunosuppressive regimens on patients with rapidly progressive glomerulonephritis.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Trental

Condition Name

Condition Name for Trental
Intervention Trials
Inflammation 2
Type 2 Diabetes Mellitus 1
Capsular Contractures 1
Impotence 1
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Condition MeSH

Condition MeSH for Trental
Intervention Trials
Kidney Diseases 5
Renal Insufficiency, Chronic 4
Necrosis 3
Depressive Disorder 3
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Clinical Trial Locations for Trental

Trials by Country

Trials by Country for Trental
Location Trials
United States 29
Egypt 6
Taiwan 3
Mexico 2
Canada 2
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Trials by US State

Trials by US State for Trental
Location Trials
Minnesota 3
Texas 3
Ohio 3
Missouri 2
District of Columbia 2
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Clinical Trial Progress for Trental

Clinical Trial Phase

Clinical Trial Phase for Trental
Clinical Trial Phase Trials
Phase 4 7
Phase 3 8
Phase 2/Phase 3 2
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Clinical Trial Status

Clinical Trial Status for Trental
Clinical Trial Phase Trials
Completed 20
Recruiting 8
Unknown status 7
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Clinical Trial Sponsors for Trental

Sponsor Name

Sponsor Name for Trental
Sponsor Trials
Ain Shams University 3
National Taiwan University Hospital 3
Arak University of Medical Sciences 2
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Sponsor Type

Sponsor Type for Trental
Sponsor Trials
Other 72
Industry 8
NIH 4
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McKesson
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Colorcon

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