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Last Updated: January 18, 2020

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CLINICAL TRIALS PROFILE FOR TRENTAL

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All Clinical Trials for Trental

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000646 Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed Hoechst Marion Roussel Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
NCT00000646 Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 1969-12-31 To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity.
NCT00561093 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed Abbott Nutrition Phase 3 2008-02-01 Study of efficiency and safety of oral nutritional supplements with anti-inflammatory and antioxidative properties combined with an appetite stimulant with anti-inflammatory properties (pentoxiphylline) in treatment of malnutrition-inflammation-cachexia syndrome in maintenance hemodialysis patients
NCT00561093 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed DaVita Dialysis Phase 3 2008-02-01 Study of efficiency and safety of oral nutritional supplements with anti-inflammatory and antioxidative properties combined with an appetite stimulant with anti-inflammatory properties (pentoxiphylline) in treatment of malnutrition-inflammation-cachexia syndrome in maintenance hemodialysis patients
NCT00561093 Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients Completed Los Angeles Biomedical Research Institute Phase 3 2008-02-01 Study of efficiency and safety of oral nutritional supplements with anti-inflammatory and antioxidative properties combined with an appetite stimulant with anti-inflammatory properties (pentoxiphylline) in treatment of malnutrition-inflammation-cachexia syndrome in maintenance hemodialysis patients
NCT00583700 Trental & Vitamin E for Radiation-Induced Fibrosis Completed University of Iowa Phase 2 2003-02-01 This study seeks to determine if a combination of Trental and Vitamin E prevents the development of radiation fibrosis in women treated with radiation for the definitive management of their breast cancer.
NCT01082003 Prevention of Capsular Contracture Using Trental and Vitamin E Unknown status Legacy Health System N/A 2009-10-01 The main purpose of this research study is to determine if the use of Trental and Vitamin E will decrease the incidence and severity of contractures (shrinking and or hardening of tissue surrounding the implant) associated with breast implant reconstruction following radiation treatment. Another goal is to find out the impact that Trental and Vitamin E have on implant loss or need for surgical intervention in the setting of chest wall radiation after reconstruction. In addition, the investigators want to evaluate the patient's sense of well being and quality of life.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Trental

Condition Name

Condition Name for Trental
Intervention Trials
Medication-related Osteonecrosis of the Jaw 1
Contrast Induced Nephropathy 1
Vertigo 1
Healthy 1
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Condition MeSH

Condition MeSH for Trental
Intervention Trials
Necrosis 3
Kidney Diseases 3
Renal Insufficiency, Chronic 2
Erectile Dysfunction 2
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Clinical Trial Locations for Trental

Trials by Country

Trials by Country for Trental
Location Trials
United States 14
Egypt 2
Netherlands 1
Turkey 1
United Kingdom 1
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Trials by US State

Trials by US State for Trental
Location Trials
Texas 2
Oregon 2
Ohio 2
Washington 1
New York 1
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Clinical Trial Progress for Trental

Clinical Trial Phase

Clinical Trial Phase for Trental
Clinical Trial Phase Trials
Phase 3 5
Phase 2 6
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for Trental
Clinical Trial Phase Trials
Not yet recruiting 6
Completed 5
Recruiting 4
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Clinical Trial Sponsors for Trental

Sponsor Name

Sponsor Name for Trental
Sponsor Trials
University of Cincinnati 2
Legacy Health System 2
Walter Reed National Military Medical Center 1
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Sponsor Type

Sponsor Type for Trental
Sponsor Trials
Other 24
Industry 6
NIH 2
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