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CLINICAL TRIALS PROFILE FOR TOPOTECAN HYDROCHLORIDE
Clinical Trials for Topotecan Hydrochloride
Trial ID | Title | Status | Sponsor | Phase | Summary |
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NCT00001333 | Phase I Study of Intrathecal Topotecan | Completed | National Cancer Institute (NCI) | Phase 1 | The purpose of this study is to determine the qualitative and quantitative toxicity of intrathecal topotecan, a topoisomerase I inhibitor, in patients with meningeal malignancies refractory to conventional therapy (radiation therapy and chemotherapy). |
NCT00002395 | Safety and Effectiveness of Topotecan HCl to Treat HIV-Infected Patients With AIDS-Related Progressive Multifocal Leukoencephalopathy (PML) | Completed | SmithKline Beecham | Phase 2 | The purpose of this study is to see if it is safe and effective to give topotecan through a vein to treat HIV-infected patients with PML, an opportunistic (AIDS-related) infection caused by a virus that infects brain tissue and causes damage to the brain and the spinal cord. Topotecan fights HIV and the JC virus (the virus that causes PML) in laboratory experiments. |
NCT00002515 | Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer | Completed | Memorial Sloan Kettering Cancer Center | Phase 2 | RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bone marrow transplantation may allow doctors to give higher doses of chemotherapy and kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy with thiotepa, carboplatin, and topotecan followed by bone marrow transplantation in treating patients who have metastatic or progressive rare cancer. |
Trial ID | Title | Status | Sponsor | Phase | Summary |
Clinical Trial Conditions for Topotecan Hydrochloride
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Clinical Trial Locations for Topotecan Hydrochloride
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Clinical Trial Progress for Topotecan Hydrochloride
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Clinical Trial Sponsors for Topotecan Hydrochloride
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