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Last Updated: October 17, 2019

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CLINICAL TRIALS PROFILE FOR TOPOSAR

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Clinical Trials for Toposar

Trial ID Title Status Sponsor Phase Start Date Summary
NCT02137096 Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal Carcinoma Recruiting University of Florida Phase 3 2014-06-01 This is a pilot study to evaluate the response rates for patients undergoing high dose conditioning chemotherapy using Etoposide, Carboplatin and Ifosfamide followed by autologous stem cell transplantation for the treatment of recurrent Nasopharyngeal Cancer (NPC) in children, adolescents, and young adults.
NCT03007147 Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Not yet recruiting National Cancer Institute (NCI) Phase 3 2017-07-01 This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.
NCT03007147 Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Not yet recruiting Children's Oncology Group Phase 3 2017-07-01 This randomized phase III trial studies how well imatinib mesylate and combination chemotherapy work in treating patients with newly diagnosed Philadelphia chromosome positive acute lymphoblastic leukemia. Imatinib mesylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imatinib mesylate and combination chemotherapy may work better in treating patients with Philadelphia chromosome positive acute lymphoblastic leukemia.
NCT03016871 Nivolumab, Ifosfamide, Carboplatin, and Etoposide as Second-Line Therapy in Treating Patients With Refractory or Relapsed Hodgkin Lymphoma Not yet recruiting National Cancer Institute (NCI) Phase 2 2017-06-01 This phase II trial studies the side effects of nivolumab and to see how well it works when given together with ifosfamide, carboplatin, and etoposide in treating patients with Hodgkin lymphoma that has come back and does not respond to treatment. Monoclonal antibodies, such as nivolumab, may interfere with the ability of cancer cells to grow and spread. Drugs used in chemotherapy, such as ifosfamide, carboplatin and etoposide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving nivolumab, ifosfamide, carboplatin and etoposide may work better in treating patients with Hodgkin lymphoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Toposar

Condition Name

Condition Name for Toposar
Intervention Trials
Refractory Diffuse Large B-Cell Lymphoma 3
Diffuse Large B-Cell Lymphoma 3
Recurrent Diffuse Large B-Cell Lymphoma 3
Recurrent Hodgkin Lymphoma 2
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Condition MeSH

Condition MeSH for Toposar
Intervention Trials
Lymphoma 12
Lymphoma, Large B-Cell, Diffuse 7
Lymphoma, B-Cell 7
Carcinoma 6
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Clinical Trial Locations for Toposar

Trials by Country

Trials by Country for Toposar
Location Trials
United States 63
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Trials by US State

Trials by US State for Toposar
Location Trials
Texas 6
Washington 5
California 5
New York 4
Pennsylvania 4
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Clinical Trial Progress for Toposar

Clinical Trial Phase

Clinical Trial Phase for Toposar
Clinical Trial Phase Trials
Phase 3 5
Phase 2/Phase 3 3
Phase 2 9
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Clinical Trial Status

Clinical Trial Status for Toposar
Clinical Trial Phase Trials
Not yet recruiting 16
Recruiting 10
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Clinical Trial Sponsors for Toposar

Sponsor Name

Sponsor Name for Toposar
Sponsor Trials
National Cancer Institute (NCI) 22
M.D. Anderson Cancer Center 3
City of Hope Medical Center 3
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Sponsor Type

Sponsor Type for Toposar
Sponsor Trials
Other 23
NIH 22
Industry 4
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