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Generated: June 19, 2019

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CLINICAL TRIALS PROFILE FOR TENOFOVIR ALAFENAMIDE FUMARATE

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Clinical Trials for Tenofovir Alafenamide Fumarate

Trial ID Title Status Sponsor Phase Summary
NCT00036634 A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients Completed Gilead Sciences Phase 1/Phase 2 This study evaluated two doses of tenofovir alafenamide versus tenofovir disoproxil fumarate (tenofovir DF).
NCT01497899 Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive Adults Completed Gilead Sciences Phase 2 This study will evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (Genvoya®; E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (Stribild®; E/C/F/TDF) FDC in HIV-1 infected, antiretroviral treatment-naive adults.
NCT01565850 D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults Completed Gilead Sciences Phase 2 This study is to evaluate the safety and efficacy darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) fixed dose combination (FDC) tablet versus darunavir (DRV)+cobicistat (COBI)+emtricitabine (FTC)/tenofovir disoproxil fumarate (TDF) in HIV-1 infected, antiretroviral treatment-naive adults as determined by the achievement of HIV-1 RNA < 50 copies/mL at Week 24.
NCT01780506 Study to Evaluate the Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Positive, Antiretroviral Treatment-Naive Adults Active, not recruiting Gilead Sciences Phase 3 This study will evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (Genvoya®; E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (Stribild®; E/C/F/TDF) FDC in HIV-1 positive, antiretroviral treatment-naive adults.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Tenofovir Alafenamide Fumarate

Condition Name

Condition Name for Tenofovir Alafenamide Fumarate
Intervention Trials
HIV-1 Infection 8
HIV 8
HIV Infections 7
Chronic Hepatitis b 6
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Condition MeSH

Condition MeSH for Tenofovir Alafenamide Fumarate
Intervention Trials
Hepatitis B 15
Hepatitis 14
HIV Infections 10
Hepatitis, Chronic 7
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Clinical Trial Locations for Tenofovir Alafenamide Fumarate

Trials by Country

Trials by Country for Tenofovir Alafenamide Fumarate
Location Trials
United States 285
China 52
Canada 40
Australia 14
United Kingdom 14
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Trials by US State

Trials by US State for Tenofovir Alafenamide Fumarate
Location Trials
California 19
Florida 17
New York 15
Missouri 14
Georgia 14
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Clinical Trial Progress for Tenofovir Alafenamide Fumarate

Clinical Trial Phase

Clinical Trial Phase for Tenofovir Alafenamide Fumarate
Clinical Trial Phase Trials
Phase 4 9
Phase 3 22
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for Tenofovir Alafenamide Fumarate
Clinical Trial Phase Trials
Active, not recruiting 16
Recruiting 14
Not yet recruiting 10
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Clinical Trial Sponsors for Tenofovir Alafenamide Fumarate

Sponsor Name

Sponsor Name for Tenofovir Alafenamide Fumarate
Sponsor Trials
Gilead Sciences 29
National Institute of Allergy and Infectious Diseases (NIAID) 2
Janssen R&D Ireland 1
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Sponsor Type

Sponsor Type for Tenofovir Alafenamide Fumarate
Sponsor Trials
Industry 33
Other 25
NIH 2
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