Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients
Henry Ford Health System
For more than fifty years, vancomycin has been cited as a nephrotoxic agent. Reports of
vancomycin induced kidney injury (a.k.a vancomycin induced nephrotoxicity or VIN), have
waxed and waned throughout the years for various reasons. Recently, VIN has reemerged as a
clinical concern. This may be due to various reasons, including new dosing recommendations
as well as an increased prevalence of risk factors associated with vancomycin induced
nephrotoxicity. This study aims to evaluate a strategy which attempts to reduce kidney
damage from vancomycin use.
Pharmacodynamic of Ceftaroline and Levofloxacin Against Pathogens Associated With Community Acquired Bacterial Pneumonia
This study will further analyze the use of ceftaroline for CABP and compare its potential to
eradicate bacterial pathogens to standard fluoroquinolone therapy. The enhanced spectrum of
ceftaroline compared to levofloxacin may be further highlighted from this investigation.
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