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Last Updated: June 13, 2021

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CLINICAL TRIALS PROFILE FOR TALZENNA

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All Clinical Trials for Talzenna

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03875313 Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors Recruiting Calithera Biosciences, Inc Phase 1/Phase 2 2019-03-01 This is a Phase 1b/2 study to determine the recommended phase 2 dose (RP2D), safety and tolerability, pharmacokinetics (PK) and clinical activity of the glutaminase inhibitor CB-839 with the PARP inhibitor talazoparib in participants with advanced/metastatic solid tumors.
NCT03964532 TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer Recruiting Pfizer Phase 1/Phase 2 2019-04-17 This is a multi-institutional pilot trial for patients with advanced breast cancer. The trial is designed to assess the safety and tolerability of induction talazoparib followed by combination of talazoparib and avelumab. As an exploratory endpoint, the study team will evaluate the immunomodulatory effects of induction talazoparib followed by the combination of talazoparib and avelumab in patients with advanced breast cancer.
NCT03964532 TALAVE: Induction Talazoparib Followed by Combination of Talazoparib and Avelumab in Advanced Breast Cancer Recruiting Georgetown University Phase 1/Phase 2 2019-04-17 This is a multi-institutional pilot trial for patients with advanced breast cancer. The trial is designed to assess the safety and tolerability of induction talazoparib followed by combination of talazoparib and avelumab. As an exploratory endpoint, the study team will evaluate the immunomodulatory effects of induction talazoparib followed by the combination of talazoparib and avelumab in patients with advanced breast cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Talzenna

Condition Name

Condition Name for Talzenna
Intervention Trials
Breast Cancer 5
Triple Negative Breast Cancer 3
Solid Tumor 2
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Condition MeSH

Condition MeSH for Talzenna
Intervention Trials
Breast Neoplasms 6
Triple Negative Breast Neoplasms 4
Colorectal Neoplasms 2
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Clinical Trial Locations for Talzenna

Trials by Country

Trials by Country for Talzenna
Location Trials
United States 13
Denmark 1
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Trials by US State

Trials by US State for Talzenna
Location Trials
Massachusetts 3
Texas 3
Rhode Island 1
New York 1
Ohio 1
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Clinical Trial Progress for Talzenna

Clinical Trial Phase

Clinical Trial Phase for Talzenna
Clinical Trial Phase Trials
Phase 2 8
Phase 1/Phase 2 5
Phase 1 5
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Clinical Trial Status

Clinical Trial Status for Talzenna
Clinical Trial Phase Trials
Not yet recruiting 15
Recruiting 3
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Clinical Trial Sponsors for Talzenna

Sponsor Name

Sponsor Name for Talzenna
Sponsor Trials
Pfizer 11
Genentech, Inc. 3
National Cancer Institute (NCI) 3
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Sponsor Type

Sponsor Type for Talzenna
Sponsor Trials
Industry 25
Other 19
NIH 3
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