Last Updated: November 8, 2026

CLINICAL TRIALS PROFILE FOR TYLENOL WITH NAPROXEN

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All Clinical Trials for TYLENOL WITH NAPROXEN

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00615875 ↗ Naproxen for Acute Pain After Surgery: A Randomized, Placebo-Controlled Trial Unknown status Hamilton Health Sciences Corporation Phase 4 2008-03-01 The purpose of this study is to determine whether using an additional 48 hours of oral naproxen, after other post-operative pain medications have been stopped, will be effective in reducing opiate pain medication requirements and contribute to improved pain management.
NCT01275911 ↗ Non-opioid Analgesia for Fast-track Surgery Completed McGill University Health Center N/A 2009-01-01 In this randomized observer-blinded trial the analgesic efficacy of intravenous esmolol, as alternative to intraoperative opioids, is tested in patients undergoing laparoscopic prostatectomy and upper gastrointestinal surgery (such as Nissen fundoplication). The purpose of this study is to determine whether intravenous esmolol improves postoperative analgesia and accelerate the surgical recovery. We hypothesize that patients receiving intravenous esmolol will consume less analgesic in the postoperative period, will have less opioid-related side effects and will recover their functional status faster then patients receiving intravenous esmolol. Patients will be stratified according to the type of surgical procedure in 2 arms: 40 patients with prostate cancer and undergoing elective laparoscopic prostatectomy, and 40 patients with gastro-esophageal reflux undergoing upper gastrointestinal surgery (Nissen funduplication) will be enrolled. Patients will receive total intravenous anesthesia with propofol and esmolol (Esmolol group, n=20 in each arm) or propofol and remifentanil (Remifentanil Group, n=20 in each arm).
NCT01275911 ↗ Non-opioid Analgesia for Fast-track Surgery Completed McGill University Health Centre/Research Institute of the McGill University Health Centre N/A 2009-01-01 In this randomized observer-blinded trial the analgesic efficacy of intravenous esmolol, as alternative to intraoperative opioids, is tested in patients undergoing laparoscopic prostatectomy and upper gastrointestinal surgery (such as Nissen fundoplication). The purpose of this study is to determine whether intravenous esmolol improves postoperative analgesia and accelerate the surgical recovery. We hypothesize that patients receiving intravenous esmolol will consume less analgesic in the postoperative period, will have less opioid-related side effects and will recover their functional status faster then patients receiving intravenous esmolol. Patients will be stratified according to the type of surgical procedure in 2 arms: 40 patients with prostate cancer and undergoing elective laparoscopic prostatectomy, and 40 patients with gastro-esophageal reflux undergoing upper gastrointestinal surgery (Nissen funduplication) will be enrolled. Patients will receive total intravenous anesthesia with propofol and esmolol (Esmolol group, n=20 in each arm) or propofol and remifentanil (Remifentanil Group, n=20 in each arm).
NCT02026141 ↗ Can Dexmedetomidine For Procedural Sedation In Knee Arthroplasty Reduce Postoperative Pain? A Randomized Control Study Completed University of Saskatchewan Phase 4 2013-12-01 Dexmedetomidine has been often used for procedural sedation. It has also has been shown to have a pain sparing effect. Therefore the investigators propose that if Dexmedetomidine is used for sedation in total knee replacements done under spinal anesthetic, the patients will have less pain up to 24 hours after the procedure.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for TYLENOL WITH NAPROXEN

Condition Name

Condition Name for TYLENOL WITH NAPROXEN
Intervention Trials
Pain, Postoperative 2
Surgery--Complications 1
HIV Infected Population With Latent Tuberculosis 1
Total Knee Arthroplasty 1
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Condition MeSH

Condition MeSH for TYLENOL WITH NAPROXEN
Intervention Trials
Pain, Postoperative 4
Tuberculosis 1
Latent Tuberculosis 1
Osteoarthritis 1
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Clinical Trial Locations for TYLENOL WITH NAPROXEN

Trials by Country

Trials by Country for TYLENOL WITH NAPROXEN
Location Trials
United States 8
Canada 5
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Trials by US State

Trials by US State for TYLENOL WITH NAPROXEN
Location Trials
Illinois 2
Oklahoma 1
Texas 1
Ohio 1
Florida 1
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Clinical Trial Progress for TYLENOL WITH NAPROXEN

Clinical Trial Phase

Clinical Trial Phase for TYLENOL WITH NAPROXEN
Clinical Trial Phase Trials
PHASE4 1
Phase 4 5
Phase 3 1
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Clinical Trial Status

Clinical Trial Status for TYLENOL WITH NAPROXEN
Clinical Trial Phase Trials
Completed 4
Unknown status 3
NOT_YET_RECRUITING 1
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Clinical Trial Sponsors for TYLENOL WITH NAPROXEN

Sponsor Name

Sponsor Name for TYLENOL WITH NAPROXEN
Sponsor Trials
University of Saskatchewan 1
Lawson Health Research Institute 1
National Institutes of Health Clinical Center (CC) 1
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Sponsor Type

Sponsor Type for TYLENOL WITH NAPROXEN
Sponsor Trials
Other 10
NIH 3
Industry 1
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