CLINICAL TRIALS PROFILE FOR TRIESENCE
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All Clinical Trials for TRIESENCE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00853905 ↗ | Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? | Completed | Alcon Research | Phase 2/Phase 3 | 2009-02-01 | The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure. |
| NCT00853905 ↗ | Will the Use of Triesence During Glaucoma Surgery Provide Lower Eye Pressure and Improve the Results of the Surgery? | Completed | Wills Eye | Phase 2/Phase 3 | 2009-02-01 | The investigators hypothesize that intracameral Triesence during glaucoma surgery will provide lower intraocular pressure through better control of ocular inflammation, thus leading to a more successful filtering procedure. |
| NCT01572350 ↗ | Safety and Efficacy of Triamcinolone Acetonide Combined With Laser, Bevacizumab Combined With Laser Versus Laser Alone for the Treatment of Diffuse Non-tractional Diabetic Macular Edema | Completed | Hospital Universitario de Canarias | Phase 3 | 2010-10-01 | This clinical trial is designed to investigate differences in terms of efficacy (mean change in best corrected visual acuity obtained after 12 months of treatment) and safety, of 3 therapeutic estrategies for non-tractional macular edema in diabetic patients: a) laser alone; b) laser plus tiramcinolon; and c) laser plus bevacizumab. |
| NCT01789320 ↗ | Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis | Completed | Clearside Biomedical, Inc. | Phase 1/Phase 2 | 2013-02-01 | This study is designed to determine the safety and tolerability of a single microinjection of triamcinolone acetonide (TRIESENCE®) into the suprachoroidal space (SCS) of patients who have non-infectious uveitis. |
| NCT02221453 ↗ | Cytokine Levels in Patients With Persistent Diabetic Macular Edema Treated With Triamcinolone Acetonide | Completed | St. Michael's Hospital, Toronto | Phase 2 | 2015-09-01 | Diabetic macular edema refers to swelling (fluid accumulation) in the center of the retina. The retina is like the film of a camera and is located in the back of the eye. This condition can develop in diabetics where swelling results from leaking of fluid from the blood vessels of the eye, into the center of the retina, the macula. If left untreated, this can affect central vision. The current standard treatment for diabetic macular edema includes medications injected directly into the eye (intravitreal injections) and laser eye treatment. The drugs that are injected directly into the eye are known as anti-Vascular Endothelial Growth Factor (anti-VEGF) agents which help to reduce the leaking. This includes bevacizumab (Avastin®) and ranibizumab (Lucentis®). However, some patients do not respond well to these anti-VEGF treatments will be given the option of switching to an another class of medications, called steroids. Triamcinolone acetonide is one of these steroids and is also injected directly into the eye. These steroids will help reduce inflammation and possibly as a consequence, reduce swelling in the eye. The purpose of this study is to determine what cellular factors affect a patient's treatment response (amount of swelling reduction) following triamcinolone acetonide intravitreal injections for diabetic macular edema. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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