CLINICAL TRIALS PROFILE FOR TRENTAL
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All Clinical Trials for TRENTAL
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00000646 ↗ | Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS | Completed | Hoechst Marion Roussel | Phase 1 | 1969-12-31 | To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity. |
NCT00000646 ↗ | Pentoxifylline (Trental) as a Modulator of Tumor Necrosis Factor and of HIV Replication in Patients With AIDS | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 | 1969-12-31 | To determine whether pentoxifylline lowers tumor necrosis factor (TNF) levels in AIDS patients. Pentoxifylline decreases tumor necrosis factor (TNF), and therefore should decrease such TNF-intensified events as cachexia, enhanced HIV expression, and inhibition of zidovudine (AZT) activity. |
NCT00243789 ↗ | Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular Dystrophy | Completed | Cooperative International Neuromuscular Research Group | Phase 1/Phase 2 | 2005-09-01 | The purpose of this study is to see if male children with Duchenne muscular dystrophy (DMD) have changes in strength when given the drug Pentoxifylline as a rescue treatment. A total of 64 subjects are expected to participate through all other centers of the Cooperative International Neuromuscular Research Group (CINRG) worldwide. The primary purpose of this study is to see whether the addition of pentoxifylline to a steroid regimen is effective in treating deteriorating muscle strength by comparing the muscle strength of PTX treated subjects and placebo treated subjects. |
NCT00267670 ↗ | Pentoxifylline/Nonalcoholic Steatohepatitis (NASH) Study: The Effect of Pentoxifylline on NASH | Completed | Northwestern University | Phase 2/Phase 3 | 2005-03-01 | The purpose of this study is to explore the potential benefit of the medication, pentoxifylline, for the treatment of NASH. |
NCT00354198 ↗ | Efficacy of Pentoxifylline on Rapidly Progressive Glomerulonephritis | Terminated | National Science Council, Taiwan | Phase 3 | 2006-08-01 | We have recently demonstrated that pentoxifylline (PTX) has the potential to treat severe glomerular inflammation in a rat model of accelerated anti-glomerular basement membrane (GBM) glomerulonephritis. This study aims to investigate the therapeutic effects of combined PTX and conventional immunosuppressive regimens on patients with rapidly progressive glomerulonephritis. |
NCT00354198 ↗ | Efficacy of Pentoxifylline on Rapidly Progressive Glomerulonephritis | Terminated | National Taiwan University Hospital | Phase 3 | 2006-08-01 | We have recently demonstrated that pentoxifylline (PTX) has the potential to treat severe glomerular inflammation in a rat model of accelerated anti-glomerular basement membrane (GBM) glomerulonephritis. This study aims to investigate the therapeutic effects of combined PTX and conventional immunosuppressive regimens on patients with rapidly progressive glomerulonephritis. |
NCT00354731 ↗ | Efficacy of Pentoxifylline on Primary Nephrotic Syndrome | Completed | National Science Council, Taiwan | Phase 3 | 2006-08-01 | We aim to investigate (1) the effects of combined pentoxifylline and corticosteroids, compared to that of corticosteroids, on patients with primary nephrotic syndrome; and if possible (2) the effects of pentoxifylline monotherapy on patients with primary nephrotic syndrome not suitable for or intolerant of standard corticosteroid therapy. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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