Dichotic Listening as a Predictor of Medication Response in Depression
Completed
New York State Psychiatric Institute
Phase 1/Phase 2
1994-04-01
Depressed patients will have hearing tests and then be treated with up to three treatments
(i.e., Fluoxetine, Imipramine) until remitted, to see whether test results predict specific
outcomes.
Dichotic Listening as a Predictor of Medication Response in Depression
Completed
New York State Psychiatric Institute
Phase 4
2006-07-01
This study will recruit 100 depressed patients to test whether the previous finding of an
association between treatment response (with treatment groups including placebo, imipramine,
and fluoxetine) and preferences of hemispheric laterality in perceptual processing are also
found with a different type of commonly used anti-depressant, bupropion.
To Demonstrate the Relative Bioavailability of Sandoz Inc. and Tyco Healthcare (Tofranil) 50 mg Imipramine Hydrochloride Tablets In Healthy Adults Volunteers Under Fasting Conditions
Completed
Sandoz
Phase 1
2005-07-01
To demonstrate the relative bioavailability of Sandoz Inc. and Tyco Healthcare (Tofranil) 50
mg imipramine hydrochloride tablets in healthy adult volunteers under fasting conditions.
Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters
Completed
Astellas Pharma Inc
N/A
2010-04-01
Lower urinary tract symptoms such as urinary leakage and overactive bladder affect millions
of American women. Women may develop these problems because the innervation of the muscles of
the bladder and urethra are injured. Most research on treating these problems has focused on
the abnormalities of the bladder muscle, but newer studies have shown abnormalities in the
innervation and muscle function of the urethra.
Women with these symptoms may benefit from treatment with medications to improve their
urethral function. However, to truly understand what types of medications will help women
with these symptoms, the investigators wish to study how these medications affect innervation
and muscle function in healthy women who do not have lower urinary tract symptoms.
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