Last Updated: October 28, 2026

CLINICAL TRIALS PROFILE FOR SUZETRIGINE


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All Clinical Trials for Suzetrigine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT06176196 ↗ Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR) Recruiting Vertex Pharmaceuticals Incorporated Phase 2 2023-12-13 The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.
NCT06336096 ↗ A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine COMPLETED Vertex Pharmaceuticals Incorporated PHASE1 2024-03-28 The purpose of this study is to evaluate the pharmacokinetics (PK) of suzetrigine (SUZ; VX-548) and its metabolite along with its safety and tolerability, in healthy participants.
NCT06628908 ↗ Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy RECRUITING Vertex Pharmaceuticals Incorporated PHASE3 2024-10-01 The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
NCT06696443 ↗ Evaluation of the Long-term Safety and Effectiveness of Suzetrigine (SUZ) in Participants With Painful Diabetic Peripheral Neuropathy (DPN) ENROLLING_BY_INVITATION Vertex Pharmaceuticals Incorporated PHASE3 2024-12-18 The purpose of this study is to evaluate the long-term safety and tolerability of SUZ and long-term effectiveness of SUZ in treating pain associated with DPN.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Suzetrigine

Condition Name

Condition Name for Suzetrigine
Intervention Trials
Pain 4
Diabetic Peripheral Neuropathic Pain 3
Acute Pain 2
Randomized Controlled Trials 1
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Condition MeSH

Condition MeSH for Suzetrigine
Intervention Trials
Pain 6
Pain, Postoperative 3
Acute Pain 3
Agnosia 2
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Clinical Trial Locations for Suzetrigine

Trials by Country

Trials by Country for Suzetrigine
Location Trials
United States 102
New Zealand 1
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Trials by US State

Trials by US State for Suzetrigine
Location Trials
Arizona 6
Utah 5
Texas 5
Florida 5
Virginia 4
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Clinical Trial Progress for Suzetrigine

Clinical Trial Phase

Clinical Trial Phase for Suzetrigine
Clinical Trial Phase Trials
PHASE4 7
PHASE3 5
PHASE2 1
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Clinical Trial Status

Clinical Trial Status for Suzetrigine
Clinical Trial Phase Trials
NOT_YET_RECRUITING 8
COMPLETED 5
RECRUITING 4
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Clinical Trial Sponsors for Suzetrigine

Sponsor Name

Sponsor Name for Suzetrigine
Sponsor Trials
Vertex Pharmaceuticals Incorporated 9
Latigo Biotherapeutics 2
Jacob Lensing 1
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Sponsor Type

Sponsor Type for Suzetrigine
Sponsor Trials
Industry 11
OTHER 8
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