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CLINICAL TRIALS PROFILE FOR SOTALOL HYDROCHLORIDE

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Clinical Trials for Sotalol Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00000464	Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3	To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000464	Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)	Completed	University of Washington	Phase 3	To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000518	Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3	To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000518	Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)	Completed	University of Utah	Phase 3	To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000531	Antiarrhythmics Versus Implantable Defibrillators (AVID)	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3	To evaluate if use of an implantable cardiac defibrillator (ICD) results in reduction in total mortality, when compared with conventional pharmacological therapy, in patients resuscitated from sudden cardiac death who are otherwise at very high risk of mortality from arrhythmic causes.

Clinical Trial Conditions for Sotalol Hydrochloride

Condition Name

Condition Name for Sotalol Hydrochloride
Intervention	Trials
Atrial Fibrillation	10
Cardiovascular Diseases	4
Ventricular Tachycardia	4
Arrhythmia	4

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Condition MeSH

Condition MeSH for Sotalol Hydrochloride
Intervention	Trials
Atrial Fibrillation	12
Tachycardia	9
Tachycardia, Ventricular	7
Heart Diseases	5

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Clinical Trial Locations for Sotalol Hydrochloride

Trials by Country

Trials by Country for Sotalol Hydrochloride
Location	Trials
United States	87
Canada	16
France	3
United Kingdom	3
Italy	2

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Trials by US State

Trials by US State for Sotalol Hydrochloride
Location	Trials
Ohio	4
Texas	4
Pennsylvania	4
Massachusetts	4
California	4

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Clinical Trial Progress for Sotalol Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Sotalol Hydrochloride
Clinical Trial Phase	Trials
Phase 4	9
Phase 3	11
Phase 2	2

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Clinical Trial Status

Clinical Trial Status for Sotalol Hydrochloride
Clinical Trial Phase	Trials
Completed	15
Recruiting	6
Active, not recruiting	3

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Clinical Trial Sponsors for Sotalol Hydrochloride

Sponsor Name

Sponsor Name for Sotalol Hydrochloride
Sponsor	Trials
National Heart, Lung, and Blood Institute (NHLBI)	4
Medtronic	2
VA Office of Research and Development	2

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Sponsor Type

Sponsor Type for Sotalol Hydrochloride
Sponsor	Trials
Other	36
Industry	12
NIH	4

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