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Last Updated: January 18, 2020

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CLINICAL TRIALS PROFILE FOR SOTALOL HYDROCHLORIDE

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All Clinical Trials for Sotalol Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000464 Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1987-04-01 To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000464 Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) Completed University of Washington Phase 3 1987-04-01 To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000518 Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1985-07-01 To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000518 Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) Completed University of Utah Phase 3 1985-07-01 To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000531 Antiarrhythmics Versus Implantable Defibrillators (AVID) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1992-09-01 To evaluate if use of an implantable cardiac defibrillator (ICD) results in reduction in total mortality, when compared with conventional pharmacological therapy, in patients resuscitated from sudden cardiac death who are otherwise at very high risk of mortality from arrhythmic causes.
NCT00000556 Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1995-03-01 To compare two standard treatment strategies for atrial fibrillation: ventricular rate control and anticoagulation vs. rhythm control and anticoagulation.
NCT00007605 Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm Completed VA Office of Research and Development Phase 3 1998-04-01 Atrial fibrillation is the most frequently occurring cardiac arrhythmia, with 1.0-1.5 million cases annually. It is a risk factor for congestive heart failure, and stroke, 75,000 cases of the latter occurring annually in patients with atrial fibrillation. The safety of the most widely used antiarrhythmic agent for this group of patients, quinidine, has been called into question. This study seeks to determine whether two other agents, amiodarone and sotalol, are safe and effective treatments for patients with atrial fibrillation.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Sotalol Hydrochloride

Condition Name

Condition Name for Sotalol Hydrochloride
Intervention Trials
Atrial Fibrillation 10
Arrhythmia 5
Heart Diseases 4
Ventricular Tachycardia 4
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Condition MeSH

Condition MeSH for Sotalol Hydrochloride
Intervention Trials
Atrial Fibrillation 12
Tachycardia 10
Tachycardia, Ventricular 8
Heart Diseases 5
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Clinical Trial Locations for Sotalol Hydrochloride

Trials by Country

Trials by Country for Sotalol Hydrochloride
Location Trials
United States 89
Canada 16
France 3
United Kingdom 3
Italy 2
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Trials by US State

Trials by US State for Sotalol Hydrochloride
Location Trials
Ohio 4
Virginia 4
Texas 4
Tennessee 4
Pennsylvania 4
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Clinical Trial Progress for Sotalol Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Sotalol Hydrochloride
Clinical Trial Phase Trials
Phase 4 10
Phase 3 12
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for Sotalol Hydrochloride
Clinical Trial Phase Trials
Completed 15
Recruiting 8
Not yet recruiting 4
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Clinical Trial Sponsors for Sotalol Hydrochloride

Sponsor Name

Sponsor Name for Sotalol Hydrochloride
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 4
Medtronic 2
VA Office of Research and Development 2
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Sponsor Type

Sponsor Type for Sotalol Hydrochloride
Sponsor Trials
Other 40
Industry 12
NIH 4
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