CLINICAL TRIALS PROFILE FOR SENSORCAINE
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All Clinical Trials for Sensorcaine
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00915473 ↗ | Greater Occipital Nerve Block for Migraine Prophylaxis | Completed | National Center for Advancing Translational Science (NCATS) | Phase 4 | 2009-06-01 | Migraine is a common neurological condition that can be disabling, particularly if chronic. Greater occipital nerve (GON) block has been utilized for decades for the treatment of migraine in the absence of a single randomized, placebo-controlled trial documenting its effectiveness. Hypothesis: Greater occipital nerve block reduces the frequency of days with moderate or severe headache in patients with episodic or chronic migraine. |
| NCT00915473 ↗ | Greater Occipital Nerve Block for Migraine Prophylaxis | Completed | Mayo Clinic | Phase 4 | 2009-06-01 | Migraine is a common neurological condition that can be disabling, particularly if chronic. Greater occipital nerve (GON) block has been utilized for decades for the treatment of migraine in the absence of a single randomized, placebo-controlled trial documenting its effectiveness. Hypothesis: Greater occipital nerve block reduces the frequency of days with moderate or severe headache in patients with episodic or chronic migraine. |
| NCT01073995 ↗ | The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery | Completed | Horizon Health Network | Phase 3 | 2010-03-01 | The median Orthopaedic surgery wait time in Canada is 36.7 weeks (Esmail 2008), thus there is a need to find alternative treatments for pathologies such as lumbar disc herniations (LDH). The literature has demonstrated that selective nerve root injections (SNRI) are able to alleviate sciatic symptoms caused by LDH (Riew 2006) and may be beneficial as an alternative to surgery. It is necessary to determine whether SNRIs provide significant symptom resolution alleviating the need for surgery, or to determine if their success is transient and delays the time to surgery. The purpose of the proposed study is to evaluate the success of SNRI in patients suffering with LDH and to determine which factors influence outcome. Over the span of 2 years, data from 100 patients will be collected. These patients will be surgical candidates and have exhausted all non-operative measures prior to receiving a SNRI. Upon first assessment, each eligible patient will be randomly assigned to the treatment (steroid) or control (saline) group. The patient and all treating physicians will be blinded to the treatment given. Each patient will be followed over their course of treatment and information pertaining to their pain and symptoms will be recorded using standard questionnaires. Patient demographics, diagnosis, Worker's Compensation status, spinal levels treatment/outcome, and time from referral to treatment will also be evaluated. The primary outcome measure will be defined as the avoidance of surgery. |
| NCT01615939 ↗ | A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block | Terminated | Northwestern University | Phase 4 | 2012-06-01 | The purpose of this study is to compare the incidence of postoperative symptoms of neurologic injury after a single shot infragluteal-parabiceps sciatic nerve block versus a continuous infragluteal-parabiceps sciatic nerve catheter. |
| NCT01906944 ↗ | Ultrasound Guided Transversus Abdominis Plane (TAP) vs. Trigger Point Injection (TPI) for Abdominal Wall Pain | Completed | Mayo Clinic | Phase 2 | 2012-01-01 | Patients with chronic abdominal pain- with a component of abdominal wall pain- are often treated with trigger point injections. This study will help to determine if a block within the transversus abdominis plane (TAP) will provide superior analgesic benefit to a trigger point injection as therapy for these patients. |
| NCT02044302 ↗ | A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction | Terminated | Yale University | Phase 2 | 2014-04-01 | The investigators hypothesize that in mastectomy patients with breast reconstruction, the addition of bupivacaine and botulinum toxin (BT) will result in better pain control in the acute and chronic setting, compared to traditional pain management techniques which rely almost exclusively on opioid analgesics and sedatives like diazepam (valium). This expectation is based on the fact that bupivacaine produces pre-emptive analgesia and BT will produce muscle relaxation, the combination of which will target different sites of pain generation, thus producing better analgesia. We also hypothesize that additional benefits may accrue from this regimen including decreased nausea and vomiting, sedation and constipation as a result of diminished opioid use1. |
| NCT02055053 ↗ | Effects of Local Anesthesia on Post-operative Pain During Laparoscopic Inguinal Hernia Repair | Completed | Lahey Clinic | Phase 4 | 2013-08-01 | To assess effect of local anesthetic into the preperitoneal space during laparoscopic hernia repair on post-operative pain. |
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