Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v 99mTc From Fission 99Mo
Terminated
Winnipeg Regional Health Authority
Phase 3
2016-08-01
A non-fission sourced, solvent generator produced 99mTc intravenous injection, as 99mTc -MDP,
is to be used as a bone scan diagnostic radiopharmaceutical for assessment of bone pathology
using the same oncologic indications as nuclear reactor sourced 99mTc, as 99mTc-MDP.
Sodium Pertechnetate (99Tc) Injection Generator: 99mTc From Neutron-activation 99Mo v 99mTc From Fission 99Mo
Terminated
University of Manitoba
Phase 3
2016-08-01
A non-fission sourced, solvent generator produced 99mTc intravenous injection, as 99mTc -MDP,
is to be used as a bone scan diagnostic radiopharmaceutical for assessment of bone pathology
using the same oncologic indications as nuclear reactor sourced 99mTc, as 99mTc-MDP.
An Exploratory Study of the Folic Acid-tubulysin Conjugate EC1456 in Ovarian Cancer Subjects Undergoing Surgery
Completed
Endocyte
Phase 1
2017-01-24
This study looks to enroll subjects with ovarian cancer who will be having standard of care
surgery to remove ovarian cancer tumors. The main aim of this study is to be able to observe
how EC1456 has been taken in and broken down inside tumors. The effect of EC1456 on the tumor
will also be studied. This study will also help us compare the amount of EC1456 seen in
tumors and how the tumors are imaged by the 99mTc-etarfolatide single-photon emission
tomography (SPECT) or single-photon emission tomography with in-line x-ray computed
tomography (SPECT/CT).
All subjects will undergo a 99mTc-etarfolatide SPECT or SPECT/CT scan within 2 weeks prior to
EC1456 administration.
Individual subjects will then receive 1 of the following 2 doses of EC1456 pre-operatively:
- 4 mg/m2
- 8 mg/m2
EC1456 will be administered at 1 of the following 2 time points:
-
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