Anastrozole Biphosphonate Study in Postmenopausal Women With Hormone-Receptor-Positive Early Breast Cancer
The purpose of this study is to evaluate safety parameters of anastrozole with regard to its
potential effects on postmenopausal bone loss and on lipid profiles. This trial is conducted
to investigate the effects of risedronate on BMD and on bone metabolism in postmenopausal
women using anastrozole as adjuvant therapy for hormone-receptor-positive early breast
cancer and who are high or moderate risk of fragility fracture. It is also conducted to
determine the effects of anastrozole on bone mineral density (BMD) and on bone metabolism in
women at low risk of fragility fracture.
Phase II/III Clinical Study of R484iv (Ibandronic Acid) for Primary Osteoporosis
To evaluate the efficacy and safety of R484iv by intravenous intermittent administration to
patients with primary osteoporosis in comparison with sodium risedronate hydrate (RIS) by
oral administration every day. To evaluate also the dose response of R484iv.
A Study of Actonel for the Prevention of Bone Loss
Procter and Gamble
The goal of this clinical research study is to learn if Actonel (risedronate) can help to
prevent the development of osteoporosis (brittle and weak bones) caused by the steroid
medication used to treat leukemia. The safety of this treatment in patients with ALL or LL
will also be studied.
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