Parathyroid Hormone Levels in Relation to the Phosphorus Content of Meals
National Center for Research Resources (NCRR)
Patients on hemodialysis tend to have chronic elevations in the level of phosphorus in the
blood and a secondary increase in the iPTH level. This chronic elevation in iPTH can have
adverse consequences, thus a variety of phosphate binders are given in an attempt to decrease
the absorption of phosphorus present in the normal diet. Some preliminary studies have
indicated that the iPTH level may change based on the amount of phosphorus present in a meal
prior to any significant absorption of phosphorus. If this is true in hemodialysis patients,
then the timing of the administration of phosphate binders in relation to the ingestion of
meals needs to be considered
CARE-2 (Calcium Acetate [PhosLo®]/Sevelamer[Renagel®] Evaluation Study 2) for Heart Calcification in Dialysis Patients
The purpose of the study is to evaluate the effects of two phosphate binders, PhosLo and
sevelamer, on heart calcification in dialysis patients. The study will use a non-invasive
technique, electron beam computed tomography (CT) scanning, to measure calcium in the
coronary arteries, the aortic valve, and the mitral valve.
Serving leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.