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Last Updated: April 19, 2024

CLINICAL TRIALS PROFILE FOR RECLAST


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All Clinical Trials for RECLAST

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00171964 ↗ Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions Completed Novartis Pharmaceuticals Phase 4 2002-05-01 It is the aim of this multicentric clinical study to assess the efficacy and tolerability of zoledronic acid in combination with radiotherapy in patients with advanced osteolytic bone lesions in terms of the reduction of pain and analgesic consumption.
NCT00305695 ↗ Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries Completed National Cancer Institute (NCI) Phase 2 2005-11-28 This randomized phase II trial is studying zoledronate to see how well it works compared to observation in maintaining bone mineral density in patients who are undergoing surgery to remove both ovaries. Zoledronate may prevent bone loss in patients who are undergoing surgery to remove the ovaries.
NCT00305695 ↗ Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries Completed Gynecologic Oncology Group Phase 2 2005-11-28 This randomized phase II trial is studying zoledronate to see how well it works compared to observation in maintaining bone mineral density in patients who are undergoing surgery to remove both ovaries. Zoledronate may prevent bone loss in patients who are undergoing surgery to remove the ovaries.
NCT00439647 ↗ Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis Completed Novartis Pharmaceuticals Phase 3 2006-12-01 This study will investigate if the drug zoledronic acid given once yearly is safe and has beneficial effects in treating osteoporosis by reducing bone loss and fractures in men with osteoporosis.
NCT00556374 ↗ Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy Active, not recruiting Austrian Breast and Colorectal Cancer Study Group Phase 3 2006-12-18 The purpose of this study is to determine whether denosumab compared to placebo, will reduce the rate of first clinical fracture in women with non-metastatic breast cancer receiving (non-steroidal) aromatase inhibitor therapy.
NCT00556374 ↗ Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy Active, not recruiting Amgen Phase 3 2006-12-18 The purpose of this study is to determine whether denosumab compared to placebo, will reduce the rate of first clinical fracture in women with non-metastatic breast cancer receiving (non-steroidal) aromatase inhibitor therapy.
NCT00558012 ↗ Zoledronic Acid for Osteoporosis in the Elderly Completed National Institute on Aging (NIA) N/A 2007-12-01 This trial will examine the safety, efficacy and feasibility of a single dose of intravenous zoledronic acid in the maintenance of skeletal integrity for frail, institutionalized women, who are most at risk for the deleterious outcomes of osteoporosis. The investigators will test the hypothesis that in institutionalized elderly women a single dose of intravenous zoledronic acid therapy will: (1) be efficacious as demonstrated by stability or improvement in bone mass measurements and reductions in bone turnover; (2) be safe and feasible; and (3) provide estimates for vertebral and nonvertebral fracture reduction in this cohort for use in planning a future study.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for RECLAST

Condition Name

Condition Name for RECLAST
Intervention Trials
Osteoporosis 11
Bone Loss 5
Osteoporosis, Postmenopausal 3
Breast Cancer 2
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Condition MeSH

Condition MeSH for RECLAST
Intervention Trials
Osteoporosis 17
Osteoporosis, Postmenopausal 5
Osteoporotic Fractures 3
Bone Diseases, Metabolic 3
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Clinical Trial Locations for RECLAST

Trials by Country

Trials by Country for RECLAST
Location Trials
United States 89
Canada 7
Australia 5
Spain 5
Belgium 3
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Trials by US State

Trials by US State for RECLAST
Location Trials
Pennsylvania 8
New York 5
Michigan 4
Massachusetts 4
California 4
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Clinical Trial Progress for RECLAST

Clinical Trial Phase

Clinical Trial Phase for RECLAST
Clinical Trial Phase Trials
Phase 4 14
Phase 3 3
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for RECLAST
Clinical Trial Phase Trials
Completed 14
Recruiting 7
Active, not recruiting 3
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Clinical Trial Sponsors for RECLAST

Sponsor Name

Sponsor Name for RECLAST
Sponsor Trials
National Institute on Aging (NIA) 5
Novartis Pharmaceuticals 5
National Institutes of Health (NIH) 4
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Sponsor Type

Sponsor Type for RECLAST
Sponsor Trials
Other 31
NIH 12
Industry 10
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