Low Doses of Cholestyramine in the Treatment of Hyperthyroidism
Shiraz University of Medical Sciences
The enterohepatic circulation of thyroid hormones is increased in thyrotoxicosis.Bile-salt
sequestrants (ionic exchange resins) bind thyroid hormones in the intestine and thereby
increase their fecal excretion. Based on these observations, the use of cholestyramine has
been tried. The present study evaluates the effect of low doses of cholestyramine as an
adjunctive therapy in the management of hyperthyroidism
Impact of SSKI Pre-Treatment on Blood Loss in Thyroidectomy for Graves Disease
University of Massachusetts, Worcester
The purpose of this study is to determine whether a brief course of SSKI (saturated solution
of potassium iodide) administered preoperatively provides any benefit in the surgical
management of patients undergoing thyroidectomy as definitive management of their Graves
Antithyroid Drug Treatment of Thyrotoxicosis in Young People
Newcastle-upon-Tyne Hospitals NHS Trust
The investigators aim to establish whether biochemical control during anti-thyroid drug
therapy in young people with thyrotoxicosis varies depending upon whether a 'block and
replace' or 'dose titration' regimen is used. The investigators will also assess remission
rates and the frequency of side-effects in the two treatment groups.
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