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Last Updated: May 28, 2022

CLINICAL TRIALS PROFILE FOR PROMETHAZINE HYDROCHLORIDE


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All Clinical Trials for Promethazine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00270777 ↗ Improving Safety of Antivenom in People Bitten by Snakes Completed University of Kelaniya Phase 4 2005-03-01 A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, & hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in people bitten by snakes: randomised, double blind, placebo-controlled trial.
NCT00293215 ↗ Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen Terminated Wyeth is now a wholly owned subsidiary of Pfizer Phase 1 2006-02-01 This was a Phase 1 dose-escalation study of CMD-193, a humanized monoclonal antibody linked to the toxin calicheamicin, in subjects with advanced tumors expressing the Lewis-Y antigen. The primary study objective was to determine the biodistribution and pharmacokinetics (PK) of 111-In-CMD-193 (i.e., CMD-193 tagged with a small amount of radioactive Indium [111-In]), with secondary objectives of determining changes in tumor metabolism and describing the antitumor responses to CMD-193.
NCT00293215 ↗ Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen Terminated Ludwig Institute for Cancer Research Phase 1 2006-02-01 This was a Phase 1 dose-escalation study of CMD-193, a humanized monoclonal antibody linked to the toxin calicheamicin, in subjects with advanced tumors expressing the Lewis-Y antigen. The primary study objective was to determine the biodistribution and pharmacokinetics (PK) of 111-In-CMD-193 (i.e., CMD-193 tagged with a small amount of radioactive Indium [111-In]), with secondary objectives of determining changes in tumor metabolism and describing the antitumor responses to CMD-193.
NCT00429832 ↗ A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department Completed GlaxoSmithKline Phase 4 2003-10-01 This was a trial comparing two commonly used medications for nausea and vomiting, ondansetron and promethazine, in the Emergency Department.
NCT00429832 ↗ A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department Completed University of New Mexico Phase 4 2003-10-01 This was a trial comparing two commonly used medications for nausea and vomiting, ondansetron and promethazine, in the Emergency Department.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Promethazine Hydrochloride

Condition Name

Condition Name for Promethazine Hydrochloride
Intervention Trials
Nausea 10
Pain 5
Vomiting 5
Postoperative Nausea and Vomiting 4
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Condition MeSH

Condition MeSH for Promethazine Hydrochloride
Intervention Trials
Nausea 18
Vomiting 15
Postoperative Nausea and Vomiting 8
Pain, Postoperative 4
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Clinical Trial Locations for Promethazine Hydrochloride

Trials by Country

Trials by Country for Promethazine Hydrochloride
Location Trials
United States 33
Iran, Islamic Republic of 3
Brazil 2
Germany 2
Canada 2
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Trials by US State

Trials by US State for Promethazine Hydrochloride
Location Trials
Texas 7
Pennsylvania 6
Tennessee 2
Massachusetts 2
Florida 2
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Clinical Trial Progress for Promethazine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Promethazine Hydrochloride
Clinical Trial Phase Trials
Phase 4 17
Phase 3 11
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Promethazine Hydrochloride
Clinical Trial Phase Trials
Completed 31
Terminated 9
Unknown status 6
[disabled in preview] 5
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Clinical Trial Sponsors for Promethazine Hydrochloride

Sponsor Name

Sponsor Name for Promethazine Hydrochloride
Sponsor Trials
Charleston Laboratories, Inc 5
M.D. Anderson Cancer Center 3
Merck Sharp & Dohme Corp. 2
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Sponsor Type

Sponsor Type for Promethazine Hydrochloride
Sponsor Trials
Other 59
Industry 14
U.S. Fed 1
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Colorcon
Mallinckrodt
Dow
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Johnson and Johnson
Medtronic

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