CLINICAL TRIALS PROFILE FOR PROMETHAZINE

All Clinical Trials for Promethazine

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00270777 ↗	Improving Safety of Antivenom in People Bitten by Snakes	Completed	University of Kelaniya	Phase 4	2005-03-01	A study to increase the safety of polyvalent antivenom involving 1000 patients in three centres: low dose adrenaline, promethazine, & hydrocortisone (alone and in combination) to prevent acute adverse reactions to antivenom in people bitten by snakes: randomised, double blind, placebo-controlled trial.
NCT00293215 ↗	Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen	Terminated	Wyeth is now a wholly owned subsidiary of Pfizer	Phase 1	2006-02-01	This was a Phase 1 dose-escalation study of CMD-193, a humanized monoclonal antibody linked to the toxin calicheamicin, in subjects with advanced tumors expressing the Lewis-Y antigen. The primary study objective was to determine the biodistribution and pharmacokinetics (PK) of 111-In-CMD-193 (i.e., CMD-193 tagged with a small amount of radioactive Indium [111-In]), with secondary objectives of determining changes in tumor metabolism and describing the antitumor responses to CMD-193.
NCT00293215 ↗	Biodistribution Study of CMD-193 in Patients With Advanced Tumours Expressing the Lewis-Y Antigen	Terminated	Ludwig Institute for Cancer Research	Phase 1	2006-02-01	This was a Phase 1 dose-escalation study of CMD-193, a humanized monoclonal antibody linked to the toxin calicheamicin, in subjects with advanced tumors expressing the Lewis-Y antigen. The primary study objective was to determine the biodistribution and pharmacokinetics (PK) of 111-In-CMD-193 (i.e., CMD-193 tagged with a small amount of radioactive Indium [111-In]), with secondary objectives of determining changes in tumor metabolism and describing the antitumor responses to CMD-193.
NCT00429832 ↗	A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department	Completed	GlaxoSmithKline	Phase 4	2003-10-01	This was a trial comparing two commonly used medications for nausea and vomiting, ondansetron and promethazine, in the Emergency Department.
NCT00429832 ↗	A RCT of Ondansetron and Promethazine in the Treatment of Nausea and Vomiting in the Emergency Department	Completed	University of New Mexico	Phase 4	2003-10-01	This was a trial comparing two commonly used medications for nausea and vomiting, ondansetron and promethazine, in the Emergency Department.

Clinical Trial Conditions for Promethazine

Condition Name

Condition Name for Promethazine
Intervention	Trials
Nausea	10
Pain	5
Vomiting	5
Postoperative Nausea and Vomiting	4

Condition MeSH

Condition MeSH for Promethazine
Intervention	Trials
Nausea	18
Vomiting	15
Postoperative Nausea and Vomiting	8
Pain, Postoperative	4

Clinical Trial Locations for Promethazine

Trials by Country

Trials by Country for Promethazine
Location	Trials
United States	33
Iran, Islamic Republic of	3
Lebanon	2
Australia	2
Israel	2

Trials by US State

Trials by US State for Promethazine
Location	Trials
Texas	7
Pennsylvania	6
Massachusetts	2
Florida	2
Tennessee	2

Clinical Trial Progress for Promethazine

Clinical Trial Phase

Clinical Trial Phase for Promethazine
Clinical Trial Phase	Trials
Phase 4	17
Phase 3	11
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for Promethazine
Clinical Trial Phase	Trials
Completed	31
Terminated	9
Unknown status	6

Clinical Trial Sponsors for Promethazine

Sponsor Name

Sponsor Name for Promethazine
Sponsor	Trials
Charleston Laboratories, Inc	5
M.D. Anderson Cancer Center	3
Shahid Beheshti University of Medical Sciences	2

Sponsor Type

Sponsor Type for Promethazine
Sponsor	Trials
Other	59
Industry	14
U.S. Fed	1