Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS)
Terminated
Galapagos NV
Phase 2
2009-12-01
Patients with an acute exacerbation of Relapsing-Remitting Multiple Sclerosis or with
Clinically Isolated Syndrome receive either one single infusion of Nanocort or three daily
infusions of SoluMedrol. Main objective is to assess the occurrence of new
gadolinium-enhanced T1-weighted lesions at week 8 vs week 1 after treatment.
Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis
Completed
Eyegate Pharmaceuticals, Inc.
Phase 3
2011-12-01
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with
dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery
System (EGDS) compared to prednisolone acetate ophthalmic suspension (1%) in patients with
non-infectious anterior segment uveitis.
Evaluation of the Efficacy of Topical Ophthalmic Steroids in a Modified Conjunctival Allergen Challenge (CAC) Model
Completed
ORA, Inc.
Phase 4
2012-01-01
The purpose of this study is to evaluate the effectiveness of the modified Conjunctival
Allergen Challenge (CAC) and observe how the produced allergic inflammation reacts to
treatment with a proven ocular anti-inflammatory medication,
Prednisolone, assessed by the following measures:
- Ocular itching
- Conjunctival redness
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