CLINICAL TRIALS PROFILE FOR PIMOZIDE
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All Clinical Trials for Pimozide
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00004652 ↗ | Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome | Completed | University of Rochester | Phase 2 | 1993-02-01 | OBJECTIVES: I. Determine whether the time period between randomization and endpoint is longer in the short term pimozide therapy or longer term therapy in patients with Tourette syndrome. II. Determine whether tic severity, medication side effects, academic performance and psychosocial functioning are better in the short term pimozide therapy or longer term pimozide therapy. |
NCT00004652 ↗ | Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome | Completed | National Center for Research Resources (NCRR) | Phase 2 | 1993-02-01 | OBJECTIVES: I. Determine whether the time period between randomization and endpoint is longer in the short term pimozide therapy or longer term therapy in patients with Tourette syndrome. II. Determine whether tic severity, medication side effects, academic performance and psychosocial functioning are better in the short term pimozide therapy or longer term pimozide therapy. |
NCT00158223 ↗ | Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia | Completed | National Institute of Mental Health (NIMH) | Phase 4 | 2004-10-01 | This study will assess the effectiveness of pimozide in enhancing the effects of clozapine in the treatment of schizophrenia. |
NCT00158223 ↗ | Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia | Completed | Icahn School of Medicine at Mount Sinai | Phase 4 | 2004-10-01 | This study will assess the effectiveness of pimozide in enhancing the effects of clozapine in the treatment of schizophrenia. |
NCT00289861 ↗ | Risperidone Augmentation in Patients With Schizophrenia | Completed | Stanley Medical Research Institute | Phase 4 | 2003-02-01 | We propose a double-blind, placebo-controlled trial to study the effectiveness and tolerability of adding risperidone to stable yet only partially remitted patients with schizophrenia maintained on clozapine. |
NCT00289861 ↗ | Risperidone Augmentation in Patients With Schizophrenia | Completed | Massachusetts General Hospital | Phase 4 | 2003-02-01 | We propose a double-blind, placebo-controlled trial to study the effectiveness and tolerability of adding risperidone to stable yet only partially remitted patients with schizophrenia maintained on clozapine. |
NCT00374244 ↗ | Efficacy of Pimozide Augmentation for Clozapine Partial Response | Completed | Stanley Medical Research Institute | Phase 2 | 2004-01-01 | This is a 12 week outpatient study for patients with schizophrenia who are on Clozapine, but continue to experience symptoms. The purpose of this project is to find out if small doses of pimozide (an antipsychotic medication, taken by mouth) will be helpful in reducing symptoms (such as hearing voices, having trouble in organizing your thoughts, lack of interest in life events and social activities), compared to placebo (an inactive substance, "sugar pill"), when added to clozapine in patients with schizophrenia. The participant will be asked to come in once a week to meet with the research staff and study doctor. The participant will continue to see your regular clinician during this study for all normal appointments. The participant will remain on your current medications throughout the study. During the study you will be randomly selected to be put on a small dose of Pimozide or placebo. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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