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Last Updated: October 14, 2019

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CLINICAL TRIALS PROFILE FOR PILOCARPINE HYDROCHLORIDE

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Clinical Trials for Pilocarpine Hydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003139 Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer Completed National Cancer Institute (NCI) Phase 3 1998-03-01 RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as pilocarpine may protect normal cells from the side effects of radiation therapy. It is not yet known if pilocarpine may be effective in preventing mucositis and dry mouth in patients receiving radiation therapy for head and neck cancer. PURPOSE: Randomized, double-blinded, phase III trial to study the effectiveness of pilocarpine in preventing mucositis and dry mouth in patients receiving radiation therapy for head and neck cancer.
NCT00003139 Pilocarpine in Preventing Mucositis and Dry Mouth in Patients Receiving Radiation Therapy for Head and Neck Cancer Completed Radiation Therapy Oncology Group Phase 3 1998-03-01 RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as pilocarpine may protect normal cells from the side effects of radiation therapy. It is not yet known if pilocarpine may be effective in preventing mucositis and dry mouth in patients receiving radiation therapy for head and neck cancer. PURPOSE: Randomized, double-blinded, phase III trial to study the effectiveness of pilocarpine in preventing mucositis and dry mouth in patients receiving radiation therapy for head and neck cancer.
NCT00003686 Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids Terminated NCIC Clinical Trials Group Phase 3 1998-08-01 RATIONALE: Pilocarpine may help to relieve dry mouth in patients receiving opioids for cancer therapy. It is not yet known whether pilocarpine is more effective than no further treatment for this condition. PURPOSE: Randomized phase III trial to determine the effectiveness of pilocarpine in treating patients who have dry mouth caused by opioids.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pilocarpine Hydrochloride

Condition Name

Condition Name for Pilocarpine Hydrochloride
Intervention Trials
Dry Mouth 5
Xerostomia 4
Glaucoma 4
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Condition MeSH

Condition MeSH for Pilocarpine Hydrochloride
Intervention Trials
Glaucoma 6
Xerostomia 6
Head and Neck Neoplasms 3
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Clinical Trial Locations for Pilocarpine Hydrochloride

Trials by Country

Trials by Country for Pilocarpine Hydrochloride
Location Trials
United States 89
Canada 11
United Kingdom 2
Germany 2
Korea, Republic of 2
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Trials by US State

Trials by US State for Pilocarpine Hydrochloride
Location Trials
Texas 6
California 4
New York 4
Colorado 4
Massachusetts 3
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Clinical Trial Progress for Pilocarpine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Pilocarpine Hydrochloride
Clinical Trial Phase Trials
Phase 4 4
Phase 3 7
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Pilocarpine Hydrochloride
Clinical Trial Phase Trials
Completed 16
Recruiting 11
Not yet recruiting 2
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Clinical Trial Sponsors for Pilocarpine Hydrochloride

Sponsor Name

Sponsor Name for Pilocarpine Hydrochloride
Sponsor Trials
Roxane Laboratories 4
National Cancer Institute (NCI) 3
Montefiore Medical Center 2
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Sponsor Type

Sponsor Type for Pilocarpine Hydrochloride
Sponsor Trials
Other 40
Industry 10
NIH 4
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