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Last Updated: June 13, 2021

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CLINICAL TRIALS PROFILE FOR PEMIGATINIB

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All Clinical Trials for Pemigatinib

Trial ID Title Status Sponsor Phase Start Date Summary
NCT03656536 A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - (FIGHT-302) Not yet recruiting Incyte Corporation Phase 3 2018-11-01 The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of participants with unresectable or metastatic cholangiocarcinoma with FGFR2 rearrangement.
NCT03822117 Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations Not yet recruiting Incyte Corporation Phase 2 2019-05-17 The purpose of this study is to evaluate the efficacy and safety of pemigatinib in participants with previously treated locally advanced/metastatic or surgically unresectable solid tumor malignancies harboring activating FGFR mutations or translocations.
NCT03914794 A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors Not yet recruiting Incyte Corporation Phase 2 2019-05-01 This phase II trial studies how well Pemigatinib (an orally administered inhibitor of fibroblast growth factor receptors 1, 2, and 3) works in non-muscle invasive bladder cancer (NMIBC) patients with recurrent tumors and a prior history of low- or intermediate-risk NMIBC tumors. Participants will receive pemigatinib for 4-6 weeks prior to standard of care transurethral resection of bladder tumor (TURBT).
NCT03914794 A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors Not yet recruiting Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 2 2019-05-01 This phase II trial studies how well Pemigatinib (an orally administered inhibitor of fibroblast growth factor receptors 1, 2, and 3) works in non-muscle invasive bladder cancer (NMIBC) patients with recurrent tumors and a prior history of low- or intermediate-risk NMIBC tumors. Participants will receive pemigatinib for 4-6 weeks prior to standard of care transurethral resection of bladder tumor (TURBT).
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pemigatinib

Condition Name

Condition Name for Pemigatinib
Intervention Trials
Metastatic Cholangiocarcinoma 2
Unresectable Cholangiocarcinoma 2
Metastatic Colorectal Carcinoma 1
FGFR2 Gene Translocation 1
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Condition MeSH

Condition MeSH for Pemigatinib
Intervention Trials
Carcinoma 3
Carcinoma, Transitional Cell 3
Neoplasms 3
Cholangiocarcinoma 3
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Clinical Trial Locations for Pemigatinib

Trials by Country

Trials by Country for Pemigatinib
Location Trials
United States 11
Italy 1
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Trials by US State

Trials by US State for Pemigatinib
Location Trials
Wisconsin 2
Oregon 1
Tennessee 1
North Carolina 1
Missouri 1
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Clinical Trial Progress for Pemigatinib

Clinical Trial Phase

Clinical Trial Phase for Pemigatinib
Clinical Trial Phase Trials
Phase 3 1
Phase 2 10
Phase 1 3
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Clinical Trial Status

Clinical Trial Status for Pemigatinib
Clinical Trial Phase Trials
Not yet recruiting 14
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Clinical Trial Sponsors for Pemigatinib

Sponsor Name

Sponsor Name for Pemigatinib
Sponsor Trials
Incyte Corporation 8
Innovent Biologics (Suzhou) Co. Ltd. 2
Academic and Community Cancer Research United 2
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Sponsor Type

Sponsor Type for Pemigatinib
Sponsor Trials
Industry 12
Other 10
NIH 2
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Serving leading biopharmaceutical companies globally:

Merck
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Mallinckrodt
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Colorcon

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