CLINICAL TRIALS PROFILE FOR PARNATE

All Clinical Trials for Parnate

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00223691 ↗	Treatment of Orthostatic Hypotension in Autonomic Failure	Completed	Vanderbilt University	Phase 1	2002-03-01	The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00223691 ↗	Treatment of Orthostatic Hypotension in Autonomic Failure	Completed	Vanderbilt University Medical Center	Phase 1	2002-03-01	The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00296686 ↗	Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression	Terminated	New York State Psychiatric Institute	Phase 4	2001-09-01	This pilot study will assess the efficacy of several sequential pharmacological treatments for patients with Refractory Depression.

Clinical Trial Conditions for Parnate

Condition Name

Condition Name for Parnate
Intervention	Trials
1. Major Depressive Disorder	1
1. Major Depressive Disorder.	1
Autonomic Failure	1

Condition MeSH

Condition MeSH for Parnate
Intervention	Trials
Depressive Disorder	4
Depression	4
Depressive Disorder, Major	3

Clinical Trial Locations for Parnate

Trials by Country

Trials by Country for Parnate
Location	Trials
United States	6

Trials by US State

Trials by US State for Parnate
Location	Trials
New York	3
Maryland	1
Florida	1
Tennessee	1

Clinical Trial Progress for Parnate

Clinical Trial Phase

Clinical Trial Phase for Parnate
Clinical Trial Phase	Trials
Phase 4	3
Phase 1	2
N/A	1

Clinical Trial Status

Clinical Trial Status for Parnate
Clinical Trial Phase	Trials
Completed	3
Terminated	2
Withdrawn	1

Clinical Trial Sponsors for Parnate

Sponsor Name

Sponsor Name for Parnate
Sponsor	Trials
New York State Psychiatric Institute	3
National Institute of Mental Health (NIMH)	1
Central Michigan University	1

Sponsor Type

Sponsor Type for Parnate
Sponsor	Trials
Other	7
Industry	2
NIH	1