A Multicenter, Open-label Trial to Assess Subject Preference of PARCOPA, Carbidopa/Levodopa Orally Disintegrating Tablets, Compared to Conventional Carbidopa/Levodopa Tablets in Subjects With Stable Parkinson's Disease
Completed
UCB Pharma
Phase 3
2004-01-01
The objective of this trial was to assess subject preference for PARCOPA, carbidopa/levodopa
Orally Disintegrating Tablets (ODT), compared with conventional carbidopa/levodopa tablets,
in subjects with stable Parkinson's disease.
A Single Center, Randomized, Double-blind, Crossover Pilot Trial Comparing the Onset of Action of Parcopa™ With Sinemet® in Subjects With Stable Parkinson's Disease
Completed
UCB Pharma
Phase 3
2005-06-01
To test whether Parcopa, a new Orally Disintegrating Tablet of Carbidopa-Levodopa, has a
faster onset of action, changes in the UPDRS Motor Exam score at intervals after a single
dose of Parcopa or Sinemet are being compared in 10 subjects with Parkinson's disease.
Subjects 40 years or older having idiopathic PD with Hoehn and Yahr state II or III are
eligible if taking a stable dose of < 200 mg carbidopa and < 2000 mg levodopa daily. At both
treatment visits, either Parcopa or Sinemet, plus a placebo of the opposite tablet (ODT or
conventional) are administered. The dose is the same as the subject's prestudy regimen. The
primary efficacy variable, time to onset of action, is the first postdose time when a 30%
decrease (30% improvement) in the total score is achieved. All UPDRS evaluations are done by
a rater blinded to the active treatment received by the subject.
Parcopa Versus Carbidopa-Levodopa in a Single Dose Cross-Over Comparison Study
Completed
UCB Pharma
Phase 4
2006-10-01
To find out if a single dose of Parcopa®, a form of levodopa that dissolves in your mouth,
works faster than regular oral levodopa which is swallowed, in fluctuating PD patients.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
