APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
This randomized phase III trial is studying APF530 and dexamethasone to see how well they
work compared with palonosetron and dexamethasone in preventing nausea and vomiting in
patients receiving chemotherapy for cancer.
Dexamethasone and Ondansetron Hydrochloride or Palonosetron Hydrochloride in Preventing Nausea and Vomiting in Patients Receiving Doxorubicin Hydrochloride and Cyclophosphamide For Early Stage Breast Cancer
National Cancer Institute (NCI)
RATIONALE: Antiemetic drugs, such as dexamethasone, ondansetron hydrochloride, and
palonosetron hydrochloride, may help lessen or prevent nausea and vomiting caused by
PURPOSE: This clinical trial studies how well giving dexamethasone together with ondansetron
hydrochloride or palonosetron hydrochloride works in preventing nausea and vomiting in
patients receiving doxorubicin hydrochloride and cyclophosphamide for early stage breast
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