A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer
Not yet recruiting
Lantheus Medical Imaging
Early Phase 1
2022-11-30
To learn if piflufolastat F18 can be used in imaging scans for patients with breast cancer,
HCC, or pancreatic cancer
A Pilot Study to Assess the Clinical Utility of PYLARIFY PET-CT for Detecting Metastasis in Pancreatic Cancer, Hepatocellular Carcinoma and Breast Cancer
Not yet recruiting
M.D. Anderson Cancer Center
Early Phase 1
2022-11-30
To learn if piflufolastat F18 can be used in imaging scans for patients with breast cancer,
HCC, or pancreatic cancer
This is a voluntary research study to find out how using technology including advanced
magnetic resonance imaging (MRI) and prostate-specific membrane antigen - positron emission
tomography (PSMA-PET) scan imaging, in addition to combined prostate treatment using
radiation therapy, brachytherapy (internal radiation treatment using small radioactive seeds
placed inside the body) and androgen deprivation therapy (drug therapy to suppress hormones)
can help doctors see, track and predict tumor response to treatment for prostate cancer
patients. Participation in this study will consist of radiation planning and simulation,
magnetic resonance imaging (MRI) and positron emission tomography and computed tomography
scan (PET/CT). One MRI and PSMA PET/CT scan will be done prior to the start of first external
beam radiation therapy (EBRT) fraction. At mid-treatment prior to the second brachytherapy
fraction, an MRI and PSMA PET/CT will be done. A third scan will be performed after 75%
testosterone recovery or 12 months post androgen deprivation therapy (ADT) [whichever comes
first].
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