Last Updated: July 28, 2026

CLINICAL TRIALS PROFILE FOR PINDOLOL


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All Clinical Trials for PINDOLOL

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00007592 ↗ Hypertension Screening and Treatment Program Completed US Department of Veterans Affairs 1989-06-01 Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00007592 ↗ Hypertension Screening and Treatment Program Completed VA Office of Research and Development 1989-06-01 Hypertension is one of the most common medical problems in the United States and in the VA health care system. It has been well-documented that hypertension can be effectively treated. However, there remain important unresolved clinical questions in the area of antihypertensive treatment. For example, how much is mortality affected by visit compliance, blood pressure control and type of antihypertensive agent? Or, are some regimens associated with more morbidity than others? Or, are there inexpensive regimens that are as effective as more expensive regimens? The amount of data that is available from this demonstration project (currently 6,100 patients) will help address these questions. The answers to these questions should result in better care for veterans with hypertension.
NCT00149110 ↗ Chronos: the Use of Chronobiological Treatment in Depression Completed Eli Lilly and Company N/A 2005-09-01 The primary objective of the present study is to examine whether the combination of the antidepressant duloxetine and chronotherapeutic methods (including sleep deprivation, light therapy, and maintaining a regular sleep-wake rhythm) in patient with major depression, will induce an immediate improvement from depression and whether this antidepressive effect will be maintained in the long term (29 weeks). Patient will be randomised to the above mentioned treatment or to an active group receiving exercise.
NCT00149110 ↗ Chronos: the Use of Chronobiological Treatment in Depression Completed The County of Frederiksborg N/A 2005-09-01 The primary objective of the present study is to examine whether the combination of the antidepressant duloxetine and chronotherapeutic methods (including sleep deprivation, light therapy, and maintaining a regular sleep-wake rhythm) in patient with major depression, will induce an immediate improvement from depression and whether this antidepressive effect will be maintained in the long term (29 weeks). Patient will be randomised to the above mentioned treatment or to an active group receiving exercise.
NCT00149110 ↗ Chronos: the Use of Chronobiological Treatment in Depression Completed Hillerod Hospital, Denmark N/A 2005-09-01 The primary objective of the present study is to examine whether the combination of the antidepressant duloxetine and chronotherapeutic methods (including sleep deprivation, light therapy, and maintaining a regular sleep-wake rhythm) in patient with major depression, will induce an immediate improvement from depression and whether this antidepressive effect will be maintained in the long term (29 weeks). Patient will be randomised to the above mentioned treatment or to an active group receiving exercise.
NCT00159146 ↗ Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression Terminated Tvergaards Foundation N/A 2002-08-01 This study investigates the hypothesis that pindolol can accelerate the response to antidepressants in patients with major depression treated with venlafaxine.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for PINDOLOL

Condition Name

Condition Name for PINDOLOL
Intervention Trials
Major Depression 3
Hypertension 2
Major Depressive Disorder 2
Cardiac Failure 2
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Condition MeSH

Condition MeSH for PINDOLOL
Intervention Trials
Depressive Disorder 7
Depression 6
Depressive Disorder, Major 5
Heart Failure, Diastolic 2
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Clinical Trial Locations for PINDOLOL

Trials by Country

Trials by Country for PINDOLOL
Location Trials
United States 17
Denmark 4
Spain 2
Switzerland 2
Serbia 1
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Trials by US State

Trials by US State for PINDOLOL
Location Trials
New York 3
Florida 2
California 2
North Carolina 1
Maryland 1
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Clinical Trial Progress for PINDOLOL

Clinical Trial Phase

Clinical Trial Phase for PINDOLOL
Clinical Trial Phase Trials
PHASE2 1
Phase 4 3
Phase 3 1
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Clinical Trial Status

Clinical Trial Status for PINDOLOL
Clinical Trial Phase Trials
Completed 7
Terminated 4
Enrolling by invitation 2
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Clinical Trial Sponsors for PINDOLOL

Sponsor Name

Sponsor Name for PINDOLOL
Sponsor Trials
Weill Medical College of Cornell University 2
Actimed Therapeutics Ltd 2
University Hospital, Basel, Switzerland 2
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Sponsor Type

Sponsor Type for PINDOLOL
Sponsor Trials
Other 26
Industry 9
NIH 4
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Pindolol Clinical Trials Update, Market Analysis, and Price-Pressure Projection (2026)

Last updated: July 24, 2026

What is the latest clinical trials status for pindolol (Phase 2/3, completed, recruiting, withdrawn)?

No complete, up-to-date clinical trials register dataset is available in the provided materials to support a precise status-by-phase update for pindolol across registries (e.g., ClinicalTrials.gov, EU CTR, WHO ICTRP). With no verifiable trial-level facts supplied, a trial pipeline status table cannot be produced.

How big is the pindolol market (US, EU, global) and what segments drive sales?

No reliable, source-backed market sizing figures for pindolol are provided. Without citations and hard numbers, a market quantification and segment breakdown would be speculative.

When will pindolol face generic or exclusivity-driven erosion in major markets?

No exclusivity framework is provided for pindolol, including any reference product(s), NDA/BLA IDs, Orange Book listings, patent expiration dates, or regulatory exclusivities by jurisdiction. A defensible erosion timeline by market cannot be generated without those entries.

Which patents protect pindolol in the US and Europe, and when do they expire?

No patent estate data is provided (e.g., US patent numbers, assignees, publication/application history, jurisdictional coverage, Orange Book patents, pediatric exclusivity, or use-specific claims). A patent protection and expiration schedule cannot be constructed without primary identifiers.

What is the Orange Book status of pindolol (listed patents, exclusivities, reference listed drug)?

No Orange Book/RLD identifiers or listing records are supplied. An Orange Book status summary with patent lists and exclusivity end dates cannot be produced accurately.

Are any Paragraph IV challenges filed for pindolol, and what litigation affects generic entry?

No FDA litigation, Paragraph IV notice history, settlement terms, or court docket details are provided. A generic-entry risk assessment based on litigation status cannot be produced.

What formulations and dosing strengths of pindolol exist, and which patents cover them?

No product-formulation dataset is provided, including strength-by-dosage form (tablets vs ophthalmic if applicable in certain geographies), excipient-dependent formulation patents, or manufacturing-process patents. Without product specifics and linked patent claims, formulation IP coverage cannot be mapped.

How does pindolol compare with competing beta blockers for market position and payer adoption?

No competitive landscape facts or market-share data are provided for pindolol versus carvedilol, metoprolol, propranolol, timolol, nebivolol, bisoprolol, or atenolol. A data-backed comparison requires pricing, utilization, and formulary tiering inputs that are not present.

What is the biosimilar or biologics risk for pindolol?

Pindolol is a small-molecule beta blocker; biosimilar frameworks do not apply. However, the claim requires no trial/patent data and does not require external registration facts. (No additional biosimilar risk analysis is necessary.)

How will regulatory pathway and FDA manufacturing requirements impact pindolol generic launches?

No FDA product status, facility constraints, or CMC-related precedents are provided. A launch-resilience projection cannot be made without facts on required bioequivalence, controlled-substance or class-specific manufacturing constraints, or documented deficiencies.

What pricing and reimbursement pressures are expected for pindolol from 2026 onward?

No pricing history, reimbursement regime context, or competitor price moves are provided. A projection would be speculative without referenced WAC/AWP/AWP-to-NET trends, contract pharmacy outcomes, or payer policy changes.


Key Takeaways

  • A data-backed clinical trials update cannot be produced because no trial registry facts are provided.
  • Market sizing, segment demand drivers, and geographic forecasts cannot be quantified without sourced revenue and utilization inputs.
  • Exclusivity, patent expiration, Orange Book status, and Paragraph IV litigation timelines cannot be mapped without patent and FDA listing identifiers.
  • Pricing and reimbursement projections require historic price and payer data not supplied.

FAQs

  1. How do I find the most recent pindolol clinical trial results by registry (ClinicalTrials.gov vs EU CTR)?
  2. What reference product (RLD) is listed for pindolol on the FDA Orange Book, and what patents are attached?
  3. Do pindolol patents include method-of-use claims that could delay generic substitution?
  4. What typical CMC bottlenecks affect small-molecule beta blocker generic approvals in the US?
  5. How do beta blocker formulary placements usually drive uptake for older, off-patent agents like pindolol?

References

No sources were provided in the prompt, and no external, citable identifiers or records were available to support a factual clinical/patent/market analysis.

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