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Generated: October 15, 2018

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CLINICAL TRIALS PROFILE FOR PARNATE

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Clinical Trials for PARNATE

Trial ID Title Status Sponsor Phase Summary
NCT00223691 Treatment of Orthostatic Hypotension in Autonomic Failure Recruiting Vanderbilt University Medical Center Phase 3 The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00296686 Sequential Tranylcypromine (TC), TC + Dextroamphetamine and TC + Triiodothyronine for Refractory Depression Terminated New York State Psychiatric Institute Phase 4 This pilot study will assess the efficacy of several sequential pharmacological treatments for patients with Refractory Depression.
NCT00653393 Bioavailability Study of Tranylcypromine 10mg Tablets Under Fasting Conditions Completed SFBC Ft. Myers, Inc Phase 1 To compare the single-dose Bioavailability of Tranylcypromine and Parnate
NCT00653393 Bioavailability Study of Tranylcypromine 10mg Tablets Under Fasting Conditions Completed Par Pharmaceutical, Inc. Phase 1 To compare the single-dose Bioavailability of Tranylcypromine and Parnate
NCT01031810 PET Biomarkers in Treatment Resistant Depression Terminated National Institute of Mental Health (NIMH) Phase 4 The primary objectives of the study are to test whether brain Mono Amine Oxidase-A (MAO-A) levels are elevated in patients with treatment-resistant major depression, and to explore whether MAO-A brain levels predict treatment outcome with Mono Amine Oxidase Inhibitor (MAOI) medication in this population.
NCT01031810 PET Biomarkers in Treatment Resistant Depression Terminated New York State Psychiatric Institute Phase 4 The primary objectives of the study are to test whether brain Mono Amine Oxidase-A (MAO-A) levels are elevated in patients with treatment-resistant major depression, and to explore whether MAO-A brain levels predict treatment outcome with Mono Amine Oxidase Inhibitor (MAOI) medication in this population.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for PARNATE

Condition Name

Condition Name for PARNATE
Intervention Trials
Autonomic Failure 1
1. Major Depressive Disorder. 1
To Determine the Bioavailability of Tranylcypromine 1
Orthostatic Hypotension 1
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Condition MeSH

Condition MeSH for PARNATE
Intervention Trials
Depressive Disorder 4
Depression 4
Depressive Disorder, Major 3
Depressive Disorder, Treatment-Resistant 2
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Clinical Trial Locations for PARNATE

Trials by Country

Trials by Country for PARNATE
Location Trials
United States 6
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Trials by US State

Trials by US State for PARNATE
Location Trials
New York 3
Maryland 1
Florida 1
Tennessee 1
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Clinical Trial Progress for PARNATE

Clinical Trial Phase

Clinical Trial Phase for PARNATE
Clinical Trial Phase Trials
Phase 4 3
Phase 3 1
Phase 1 1
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Clinical Trial Status

Clinical Trial Status for PARNATE
Clinical Trial Phase Trials
Terminated 2
Completed 1
Withdrawn 1
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Clinical Trial Sponsors for PARNATE

Sponsor Name

Sponsor Name for PARNATE
Sponsor Trials
New York State Psychiatric Institute 3
Sheppard Pratt Health System 1
Central Michigan University 1
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Sponsor Type

Sponsor Type for PARNATE
Sponsor Trials
Other 6
Industry 2
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Deloitte
Chubb
Covington
Johnson and Johnson
Moodys
Cerilliant
Cantor Fitzgerald
AstraZeneca

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