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Generated: December 16, 2018

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CLINICAL TRIALS PROFILE FOR OLANZAPINE AND FLUOXETINE HYDROCHLORIDE

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Clinical Trials for Olanzapine And Fluoxetine Hydrochloride

Trial ID Title Status Sponsor Phase Summary
NCT00000373 Treatment of Obsessive-Compulsive Disorder Completed National Institute of Mental Health (NIMH) Phase 4 The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
NCT00000373 Treatment of Obsessive-Compulsive Disorder Completed University of Florida Phase 4 The purpose of this study is to find the best treatment for Tourette's Syndrome (TS)-spectrum obsessive-compulsive disorder (OCD), which includes symptoms of TS, e.g., repeated and involuntary body movements (tics). There are 2 parts to this study: In Part 1, patients are placed into 1 of 2 groups based on type of OCD, determined by medical history and family member interviews. In Part 2, patients are treated with fluvoxamine (FVX) for 8 weeks. If patients do not respond to FVX alone, either haloperidol or an inactive placebo will be added to the FVX regimen; patients will take this drug combination for 4 weeks. Patients will be monitored throughout the trial.
NCT00035321 The Study of Olanzapine Plus Fluoxetine in Combination for Treatment of Treatment Resistant Depression Completed Eli Lilly and Company Phase 3 The purposes of this study are to determine: - Whether olanzapine plus fluoxetine in combination will help patients with treatment-resistant major depression. - The safety of olanzapine plus fluoxetine in combination, plus and any side effects that might be associated with the combination. - The effectiveness of olanzapine plus fluoxetine compared to olanzapine and fluoxetine alone.
NCT00188942 A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder Completed Eli Lilly and Company Phase 4 This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control subjects. Depressed patients will be treated with a combination of fluoxetine and olanzapine and undergo MRI scans before, during, and after pharmacotherapy.
NCT00188942 A Neuroimaging Investigation of Brain Activity in Major Depressive Disorder and Bipolar Disorder Completed University Health Network, Toronto Phase 4 This study employs functional magnetic resonance imaging to compare brain activation patterns during a depressive episode in patients diagnosed with bipolar disorder, major depressive disorder, and a group of healthy control subjects. Depressed patients will be treated with a combination of fluoxetine and olanzapine and undergo MRI scans before, during, and after pharmacotherapy.
NCT00191399 Bipolar Depression Study: Bipolar Depression Assessment Study on Treatment Response Completed Eli Lilly and Company Phase 4 The primary objective of this study is to assess the efficacy of olanzapine and fluoxetine combined on all the visits as compared with the baseline visit in patients with bipolar disorder, measured by the total score of the Montgomery-Asberg Depression Rating Scale (MADRS).
NCT00485771 Olanzapine/Fluoxetine Combination Versus Comparator in the Treatment of Bipolar I Depression Completed Eli Lilly and Company Phase 4 The purpose of this study is to assess olanzapine/fluoxetine combination and lamotrigine comparative efficacy, safety and tolerability in acute and longer term treatment of bipolar depression.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Olanzapine And Fluoxetine Hydrochloride

Condition Name

Condition Name for Olanzapine And Fluoxetine Hydrochloride
Intervention Trials
Bipolar Depression 3
Major Depressive Disorder 3
Bipolar Disorder 2
Treatment Resistant Depression 2
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Condition MeSH

Condition MeSH for Olanzapine And Fluoxetine Hydrochloride
Intervention Trials
Depression 10
Depressive Disorder 9
Bipolar Disorder 6
Disease 4
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Clinical Trial Locations for Olanzapine And Fluoxetine Hydrochloride

Trials by Country

Trials by Country for Olanzapine And Fluoxetine Hydrochloride
Location Trials
United States 45
Canada 5
Russian Federation 2
Puerto Rico 2
Argentina 1
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Trials by US State

Trials by US State for Olanzapine And Fluoxetine Hydrochloride
Location Trials
Pennsylvania 3
California 3
Georgia 2
Wisconsin 2
Washington 2
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Clinical Trial Progress for Olanzapine And Fluoxetine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Olanzapine And Fluoxetine Hydrochloride
Clinical Trial Phase Trials
Phase 4 7
Phase 3 3
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Olanzapine And Fluoxetine Hydrochloride
Clinical Trial Phase Trials
Completed 10
Not yet recruiting 2
Terminated 1
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Clinical Trial Sponsors for Olanzapine And Fluoxetine Hydrochloride

Sponsor Name

Sponsor Name for Olanzapine And Fluoxetine Hydrochloride
Sponsor Trials
Eli Lilly and Company 7
University Health Network, Toronto 1
Montana State University 1
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Sponsor Type

Sponsor Type for Olanzapine And Fluoxetine Hydrochloride
Sponsor Trials
Other 12
Industry 8
NIH 1
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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Boehringer Ingelheim
McKinsey
US Department of Justice
Merck
Baxter
Medtronic
Covington
Cerilliant

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