Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus
Completed
Cairo University
Phase 3
2013-06-01
The study included forty individuals divided into 3 groups. 10 control subjects, 15 oral
lichen planus (OLP) patients who were treated with topical corticosteroids and 15 oral lichen
planus (OLP) patients who were treated with topical corticosteroids and green tea tablets.
Topical Application of Curcumin Orabase in Oral Submucous Fibrosis (OSMF)
Unknown status
SVS Institute of Dental Sciences
Phase 2
2013-12-01
Curcumin (diferuloylmethane) is the chief component of the spice turmeric and is derived from
the rhizome of the East Indian plant Curcuma longa. Curcuma longais a member of the
Zingiberacae (ginger) family of botanicals and is a perennial plant that is native to
Southeast Asia. Turmeric contains a class of compounds known as the curcuminoids, comprised
of curcumin, demethoxy curcumin and bisdemethoxycurcumin.
Topical Betamethasone and Clobetasol in Orabase in Oral Lichen Planus
Unknown status
Garlapati Komali
Phase 2
2016-05-06
Oral Lichen Planus (OLP) is an autoimmune, chronic inflammatory mucocutaneous disease
characterized by pain and burning sensation. The major types of OLP are the following:
reticular, atrophic, erosive-ulcerative, bullous and pigmentous form.Its etiology remains
unclear. The presence of auto-cytotoxic T cell clones in the lesions suggests the role of
autoimmunity. Numerous treatment options of OLP include topical and systemic agents depending
on severity of lesions . Topical corticosteroids abide the mainstay of therapy,and are widely
accepted as the primary treatment of choice.Hence this study is designed to evaluate and
compare the clinical efficacy of topical Clobetasol 0.05% in orabase and Betamethasone 0.05%
in orabase in combination with Clotrimazole 1% in the management of symptomatic Oral Lichen
Planus.
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