CLINICAL TRIALS PROFILE FOR NOVOLIN R

All Clinical Trials for Novolin R

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00071448 ↗	Insulin Aspart vs. Insulin Lispro vs. Regular Insulin in Paediatric Population	Completed	Novo Nordisk A/S	Phase 3	2002-06-01	This trial is conducted in the United States of America (USA). The aim of this trial is to to determine whether insulin aspart can be used effectively and safely in paediatric patients.
NCT00487162 ↗	The Association Between Peri-Operative Hyperglycemia and Major Morbidity and Mortality	Terminated	University of Medicine and Dentistry of New Jersey	N/A	2007-06-01	Surgery induces a stress effect on the body partially through a catabolic energy state. In turn, glucose levels may rise to levels which have been associated with major morbidity (Golden, 1999) and mortality (Ouattara, 2005). An increasing body of evidence suggests that intensive insulin therapy for tight control of blood glucose levels in certain surgical and critical care patient populations may improve mortality and selected morbidity outcomes when compared to those patients receiving conventional insulin therapy and blood glucose management. More specifically, poor intra-operative blood glucose control is associated with worse outcome after cardiac surgery. Intensive insulin therapy with tight blood glucose control in surgical patients while in the ICU may reduce morbidity and mortality. Such outcome improvements would clearly provide benefits to patients, providers and payers. To date, there is scant research examining whether intensive insulin therapy for tight control of blood glucose in the perioperative period can alter outcomes for the non cardiac surgery population. The purpose of this study is to determine whether intensive insulin therapy for tight control of blood glucose in the perioperative period in non cardiac major surgery patients is associated with altered morbidity and mortality rates.
NCT00522210 ↗	Comparison of a Twice Daily Versus a Three Times Daily Insulin Regimen in Children With Type 1 Diabetes	Completed	University of Calgary	N/A	2008-03-01	The purpose of this study is to determine whether there is a difference in blood sugar control (as measured by hemoglobin A1c (HA1c)), in children given twice daily insulin injections incorporating a new long acting insulin analogue (detemir) compared to children using their current three times a day insulin injections (with intermediate and rapid acting insulin).
NCT00593255 ↗	Efficacy and Safety of Insulin Aspart in Subjects With Type 1 or Type 2 Diabetes	Completed	Novo Nordisk A/S	Phase 4	2004-07-01	This trial is conducted in Asia. The aim of this trial is to compare the efficacy of postprandial plasma glucose of two treatment regimens in Chinese subjects.
NCT00862875 ↗	Levemir-Body Composition and Energy Metabolism	Completed	McMaster University	Phase 4	2009-03-01	The objectives is to compare the changes in body composition (primary objective), diabetes parameters, energy expenditure and energy intake between Insulin detemir (Levemir® - Novolin® 4 pen) and insulin glargine (Lantus® - Solostar®) both in combination with Metformin and insulin secretagogues (SU) between baseline and after 6 months of insulin therapy in 80 type 2 diabetic patients failing on oral diabetic agents .
NCT00862875 ↗	Levemir-Body Composition and Energy Metabolism	Completed	Novo Nordisk A/S	Phase 4	2009-03-01	The objectives is to compare the changes in body composition (primary objective), diabetes parameters, energy expenditure and energy intake between Insulin detemir (Levemir® - Novolin® 4 pen) and insulin glargine (Lantus® - Solostar®) both in combination with Metformin and insulin secretagogues (SU) between baseline and after 6 months of insulin therapy in 80 type 2 diabetic patients failing on oral diabetic agents .
NCT00862875 ↗	Levemir-Body Composition and Energy Metabolism	Completed	Institut de Recherches Cliniques de Montreal	Phase 4	2009-03-01	The objectives is to compare the changes in body composition (primary objective), diabetes parameters, energy expenditure and energy intake between Insulin detemir (Levemir® - Novolin® 4 pen) and insulin glargine (Lantus® - Solostar®) both in combination with Metformin and insulin secretagogues (SU) between baseline and after 6 months of insulin therapy in 80 type 2 diabetic patients failing on oral diabetic agents .

Clinical Trial Conditions for Novolin R

Condition Name

Condition Name for Novolin R
Intervention	Trials
Type 2 Diabetes Mellitus	3
Type 1 Diabetes	2
Diabetes	2
Type 2 Diabetes	2

Condition MeSH

Condition MeSH for Novolin R
Intervention	Trials
Diabetes Mellitus	8
Diabetes Mellitus, Type 2	4
Diabetes Mellitus, Type 1	3
Hyperglycemia	2

Clinical Trial Locations for Novolin R

Trials by Country

Trials by Country for Novolin R
Location	Trials
United States	44
India	7
Italy	7
Canada	6
China	4

Trials by US State

Trials by US State for Novolin R
Location	Trials
California	3
Utah	2
Texas	2
Pennsylvania	2
New York	2

Clinical Trial Progress for Novolin R

Clinical Trial Phase

Clinical Trial Phase for Novolin R
Clinical Trial Phase	Trials
Phase 4	4
Phase 3	2
Phase 2	3

Clinical Trial Status

Clinical Trial Status for Novolin R
Clinical Trial Phase	Trials
Completed	9
Terminated	3
Withdrawn	1

Clinical Trial Sponsors for Novolin R

Sponsor Name

Sponsor Name for Novolin R
Sponsor	Trials
Novo Nordisk A/S	3
University of Calgary	2
University of California, San Francisco	1

Sponsor Type

Sponsor Type for Novolin R
Sponsor	Trials
Other	10
Industry	6