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Generated: February 20, 2019

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CLINICAL TRIALS PROFILE FOR NINLARO

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Clinical Trials for Ninlaro

Trial ID Title Status Sponsor Phase Summary
NCT01415882 Ixazomib in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib Recruiting National Cancer Institute (NCI) Phase 2 This randomized phase II trial studies how well ixazomib (ixazomib citrate) works in treating patients with multiple myeloma that has returned after a period of improvement but is not resistant to bortezomib. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
NCT01415882 Ixazomib in Treating Patients With Relapsed Multiple Myeloma That Is Not Refractory to Bortezomib Recruiting Mayo Clinic Phase 2 This randomized phase II trial studies how well ixazomib (ixazomib citrate) works in treating patients with multiple myeloma that has returned after a period of improvement but is not resistant to bortezomib. Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
NCT01864018 Ixazomib Citrate, Cyclophosphamide, and Dexamethasone in Treating Patients With Previously Untreated Symptomatic Multiple Myeloma Suspended National Cancer Institute (NCI) Phase 1/Phase 2 This phase I/II trial studies the side effects and the best dose of cyclophosphamide when given together with ixazomib and dexamethasone in treating patients with previously untreated symptomatic multiple myeloma. Drugs used in chemotherapy, such as cyclophosphamide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Ixazomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving cyclophosphamide together with ixazomib and dexamethasone may be a better treatment for multiple myeloma.
NCT01864018 Ixazomib Citrate, Cyclophosphamide, and Dexamethasone in Treating Patients With Previously Untreated Symptomatic Multiple Myeloma Suspended Mayo Clinic Phase 1/Phase 2 This phase I/II trial studies the side effects and the best dose of cyclophosphamide when given together with ixazomib and dexamethasone in treating patients with previously untreated symptomatic multiple myeloma. Drugs used in chemotherapy, such as cyclophosphamide and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Ixazomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving cyclophosphamide together with ixazomib and dexamethasone may be a better treatment for multiple myeloma.
NCT02339922 Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma Recruiting National Cancer Institute (NCI) Phase 2 This phase II trial studies how well ixazomib citrate and rituximab work in treating patients with B-cell non-Hodgkin lymphoma that grows slowly (indolent). Ixazomib citrate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, may block cancer growth in different ways by targeting certain cells. Giving ixazomib citrate together with rituximab may work better in treating indolent B-cell non-Hodgkin lymphoma.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Ninlaro

Condition Name

Condition Name for Ninlaro
Intervention Trials
Recurrent Plasma Cell Myeloma 9
Refractory Plasma Cell Myeloma 5
Plasma Cell Myeloma 4
Multiple Myeloma 4
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Condition MeSH

Condition MeSH for Ninlaro
Intervention Trials
Multiple Myeloma 21
Neoplasms, Plasma Cell 20
Lymphoma 4
Lymphoma, Mantle-Cell 3
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Clinical Trial Locations for Ninlaro

Trials by Country

Trials by Country for Ninlaro
Location Trials
United States 46
France 13
United Kingdom 8
Czechia 8
Netherlands 7
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Trials by US State

Trials by US State for Ninlaro
Location Trials
Minnesota 10
Florida 6
Michigan 3
California 3
Ohio 3
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Clinical Trial Progress for Ninlaro

Clinical Trial Phase

Clinical Trial Phase for Ninlaro
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Ninlaro
Clinical Trial Phase Trials
Recruiting 17
Not yet recruiting 12
Suspended 1
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Clinical Trial Sponsors for Ninlaro

Sponsor Name

Sponsor Name for Ninlaro
Sponsor Trials
National Cancer Institute (NCI) 16
Mayo Clinic 10
Takeda 8
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Sponsor Type

Sponsor Type for Ninlaro
Sponsor Trials
Other 28
Industry 19
NIH 16
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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Baxter
McKinsey
Mallinckrodt
Cipla
Citi
Cerilliant
Argus Health
Medtronic

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