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Last Updated: December 13, 2024

CLINICAL TRIALS PROFILE FOR NIMODIPINE


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All Clinical Trials for Nimodipine

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000280 ↗ Glutaminergic Agents for Cocaine Abuse - 5 Completed National Institute on Drug Abuse (NIDA) Phase 1 1994-09-01 The purpose of this study is to evaluate glutaminergic agents for cocaine abuse.
NCT00000280 ↗ Glutaminergic Agents for Cocaine Abuse - 5 Completed VA Connecticut Healthcare System Phase 1 1994-09-01 The purpose of this study is to evaluate glutaminergic agents for cocaine abuse.
NCT00000280 ↗ Glutaminergic Agents for Cocaine Abuse - 5 Completed Yale University Phase 1 1994-09-01 The purpose of this study is to evaluate glutaminergic agents for cocaine abuse.
NCT00000332 ↗ High Dose Nimodipine Treatment Adjunct - 1 Completed Washington D.C. Veterans Affairs Medical Center Phase 2 1998-05-01 The purpose of this study is to determine if nimodipine is more effective than placebo in reducing stimulated craving for cocaine in cocaine dependent individuals denied access to cocaine in inpatient unit.
NCT00000332 ↗ High Dose Nimodipine Treatment Adjunct - 1 Completed National Institute on Drug Abuse (NIDA) Phase 2 1998-05-01 The purpose of this study is to determine if nimodipine is more effective than placebo in reducing stimulated craving for cocaine in cocaine dependent individuals denied access to cocaine in inpatient unit.
NCT00000738 ↗ Randomized, Double-Blind, Placebo-Controlled Trial of Nimodipine for the Neurological Manifestations of HIV-1 Completed Glaxo Wellcome Phase 1 1969-12-31 PRIMARY: To assess the safety of nimodipine in the treatment of HIV-Associated Motor / Cognitive Complex (formerly AIDS dementia complex). To assess the systemic or central nervous system toxicities (e.g., rash, headache, gastrointestinal symptoms, nausea, dyspnea, muscle pain or cramp, acne) of nimodipine. SECONDARY: To assess the efficacy of nimodipine in stabilizing the progression of HIV-Associated Motor / Cognitive Complex by improvement in neuropsychological test performance, peripheral neuropathy, or other neurologic manifestations. HIV-infected patients may develop a condition known as HIV-Associated Motor / Cognitive Complex (also known as AIDS dementia complex) that causes damage to the nervous system, particularly the brain and spinal cord. Evidence exists that nimodipine protects nerve cells in culture from injury by HIV. Although nimodipine has been used in patients with other neurological problems, its safety and effectiveness in halting the progression of HIV-Associated Motor / Cognitive Complex is not yet known.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Nimodipine

Condition Name

Condition Name for Nimodipine
Intervention Trials
Subarachnoid Hemorrhage, Aneurysmal 6
Subarachnoid Hemorrhage 5
Aneurysmal Subarachnoid Hemorrhage 5
Cocaine-Related Disorders 2
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Condition MeSH

Condition MeSH for Nimodipine
Intervention Trials
Subarachnoid Hemorrhage 18
Hemorrhage 18
Vasospasm, Intracranial 4
Stroke 4
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Clinical Trial Locations for Nimodipine

Trials by Country

Trials by Country for Nimodipine
Location Trials
United States 73
Canada 13
China 9
Czechia 5
Finland 3
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Trials by US State

Trials by US State for Nimodipine
Location Trials
Maryland 5
California 5
Arizona 4
Ohio 4
North Carolina 4
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Clinical Trial Progress for Nimodipine

Clinical Trial Phase

Clinical Trial Phase for Nimodipine
Clinical Trial Phase Trials
Phase 4 8
Phase 3 6
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for Nimodipine
Clinical Trial Phase Trials
Completed 17
Recruiting 8
Terminated 6
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Clinical Trial Sponsors for Nimodipine

Sponsor Name

Sponsor Name for Nimodipine
Sponsor Trials
Edge Therapeutics Inc 3
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2
Johns Hopkins University 2
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Sponsor Type

Sponsor Type for Nimodipine
Sponsor Trials
Other 112
Industry 9
NIH 4
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