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CLINICAL TRIALS PROFILE FOR NICOTINE

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Clinical Trials for Nicotine

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00000284	Role of Metabolites in Nicotine Dependence (1) - 1	Completed	University of Minnesota - Clinical and Translational Science Institute	Phase 2	The purpose of this study is to determine the effects of cotinine with or without a transdermal nicotine replacement on tobacco withdrawal symptoms.
NCT00000284	Role of Metabolites in Nicotine Dependence (1) - 1	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	The purpose of this study is to determine the effects of cotinine with or without a transdermal nicotine replacement on tobacco withdrawal symptoms.
NCT00000288	Role of Metabolites in Nicotine Dependence (2) - 5	Completed	University of Minnesota - Clinical and Translational Science Institute	Phase 2	The purpose of this study is to determine the effects of varying doses of cotinine on cigarette self-administration.
NCT00000288	Role of Metabolites in Nicotine Dependence (2) - 5	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	The purpose of this study is to determine the effects of varying doses of cotinine on cigarette self-administration.
NCT00000289	Role of Metabolites in Nicotine Dependence (3) - 6	Completed	University of Minnesota - Clinical and Translational Science Institute	Phase 2	The purpose of this study is to determine the effects of various doses of ondansetron transdermal nicotine replacement on tobacco withdrawal symptoms.
NCT00000289	Role of Metabolites in Nicotine Dependence (3) - 6	Completed	National Institute on Drug Abuse (NIDA)	Phase 2	The purpose of this study is to determine the effects of various doses of ondansetron transdermal nicotine replacement on tobacco withdrawal symptoms.
NCT00000295	Progesterone Treatment in Female Smokers - 12	Completed	University of Minnesota - Clinical and Translational Science Institute	Phase 2	The purpose of this study is to investigate progesterone effects in female smokers

Clinical Trial Conditions for Nicotine

Condition Name

Condition Name for Nicotine
Intervention	Trials
Smoking Cessation	156
Nicotine Dependence	108
Smoking	100
Tobacco Use Disorder	83

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Condition MeSH

Condition MeSH for Nicotine
Intervention	Trials
Tobacco Use Disorder	244
Schizophrenia	48
Alcoholism	24
Substance-Related Disorders	21

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Clinical Trial Locations for Nicotine

Trials by Country

Trials by Country for Nicotine
Location	Trials
United States	782
Canada	45
Sweden	23
France	17
Germany	17

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Trials by US State

Trials by US State for Nicotine
Location	Trials
California	75
Minnesota	56
Pennsylvania	54
Connecticut	53
Texas	45

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Clinical Trial Progress for Nicotine

Clinical Trial Phase

Clinical Trial Phase for Nicotine
Clinical Trial Phase	Trials
Phase 4	136
Phase 3	75
Phase 2/Phase 3	24

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Clinical Trial Status

Clinical Trial Status for Nicotine
Clinical Trial Phase	Trials
Completed	422
Recruiting	119
Not yet recruiting	56

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Clinical Trial Sponsors for Nicotine

Sponsor Name

Sponsor Name for Nicotine
Sponsor	Trials
National Institute on Drug Abuse (NIDA)	159
National Cancer Institute (NCI)	51
Yale University	45

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Sponsor Type

Sponsor Type for Nicotine
Sponsor	Trials
Other	755
NIH	292
Industry	172

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