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Generated: December 17, 2018

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CLINICAL TRIALS PROFILE FOR NIACIN

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Clinical Trials for Niacin

Trial ID Title Status Sponsor Phase Summary
NCT00000482 Coronary Drug Project Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To determine whether regular administration of lipid modifying drugs (clofibrate, nicotinic acid, estrogen, dextrothyroxine) to men with a documented myocardial infarction would result in significant reduction in total mortality over a five year period. Secondarily, to determine whether the degree to which these drugs changed serum lipids was correlated with any effect on mortality and morbidity rates; to gain further information on the long-term prognosis of myocardial infarction (by studying the control group as intensively as the treatment group); to acquire further experience and knowledge concerning the techniques and methodology of long-term clinical trials; to determine, in a substudy, the effectiveness of aspirin, a platelet inhibitor, in reducing recurrences of myocardial infarction.
NCT00000512 Familial Atherosclerosis Treatment Study Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To compare the effects of two intensive lipid-lowering regimens with conventional therapy on coronary atherosclerosis as assessed by arteriography.
NCT00000512 Familial Atherosclerosis Treatment Study Completed University of Washington Phase 3 To compare the effects of two intensive lipid-lowering regimens with conventional therapy on coronary atherosclerosis as assessed by arteriography.
NCT00000539 Arterial Disease Multifactorial Intervention Trial (ADMIT) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To evaluate, in asymptomatic and symptomatic participants with peripheral arterial disease, the feasibility of recruitment and adherence, efficacy and safety of HDL-C raising along with effective control of LDL-C levels, antioxidant therapy, antithrombotic therapy, and their combinations.
NCT00000553 HDL-Atherosclerosis Treatment Study (HATS) Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 To measure the effects of lipid-lowering drugs and/or antioxidant vitamins on progression or regression of coronary heart disease as measured by quantitative angiography in patients with low high density lipoprotein (HDL) cholesterol.
NCT00000553 HDL-Atherosclerosis Treatment Study (HATS) Completed University of Washington Phase 3 To measure the effects of lipid-lowering drugs and/or antioxidant vitamins on progression or regression of coronary heart disease as measured by quantitative angiography in patients with low high density lipoprotein (HDL) cholesterol.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Niacin

Condition Name

Condition Name for Niacin
Intervention Trials
Dyslipidemia 21
Hypercholesterolemia 16
Atherosclerosis 12
Hyperlipidemia 9
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Condition MeSH

Condition MeSH for Niacin
Intervention Trials
Dyslipidemias 37
Hypercholesterolemia 23
Coronary Artery Disease 20
Coronary Disease 18
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Clinical Trial Locations for Niacin

Trials by Country

Trials by Country for Niacin
Location Trials
United States 209
Canada 28
Switzerland 7
Germany 5
United Kingdom 4
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Trials by US State

Trials by US State for Niacin
Location Trials
California 19
Pennsylvania 18
Maryland 13
Texas 12
North Carolina 9
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Clinical Trial Progress for Niacin

Clinical Trial Phase

Clinical Trial Phase for Niacin
Clinical Trial Phase Trials
Phase 4 42
Phase 3 36
Phase 2/Phase 3 5
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Clinical Trial Status

Clinical Trial Status for Niacin
Clinical Trial Phase Trials
Completed 97
Terminated 16
Unknown status 9
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Clinical Trial Sponsors for Niacin

Sponsor Name

Sponsor Name for Niacin
Sponsor Trials
Merck Sharp & Dohme Corp. 29
National Heart, Lung, and Blood Institute (NHLBI) 14
Abbott 10
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Sponsor Type

Sponsor Type for Niacin
Sponsor Trials
Other 126
Industry 77
NIH 29
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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Dow
Citi
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Medtronic
Boehringer Ingelheim
US Army
McKesson
AstraZeneca

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