CLINICAL TRIALS PROFILE FOR NARATRIPTAN

All Clinical Trials for Naratriptan

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00282165 ↗	Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order	Terminated	FPC De Kijvelanden, Poortugaal	Phase 4	2006-11-01	In a double blind randomized clinical trial with cross-over design, treatment using naratriptan will be compared to placebo within a group of 30 convicts with psychiatric disorders such as psychosis or psychopathy with repeated aggressive outbursts resistant to conventional psychopharmacologic and other psychotherapeutic treatment. Hypothesis is that addition of naratriptan to the individual treatment regime reduces aggression -and improves general outcome- as compared to addition of placebo and is well tolerated in this group and under these conditions.
NCT00282165 ↗	Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order	Terminated	UMC Utrecht	Phase 4	2006-11-01	In a double blind randomized clinical trial with cross-over design, treatment using naratriptan will be compared to placebo within a group of 30 convicts with psychiatric disorders such as psychosis or psychopathy with repeated aggressive outbursts resistant to conventional psychopharmacologic and other psychotherapeutic treatment. Hypothesis is that addition of naratriptan to the individual treatment regime reduces aggression -and improves general outcome- as compared to addition of placebo and is well tolerated in this group and under these conditions.
NCT00487578 ↗	Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction	Terminated	Clinvest	Phase 4	2006-10-01	The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.
NCT00487578 ↗	Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction	Terminated	GlaxoSmithKline	Phase 4	2006-10-01	The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.
NCT00487578 ↗	Naratriptan for the Treatment of Post Traumatic Headache Associated With Cognitive Dysfunction	Terminated	Cady, Roger, M.D.	Phase 4	2006-10-01	The purpose of this study is to determine whether naratriptan, a medication approved for treatment of migraine, is effective in the treatment of post traumatic headache associated with cognitive dysfunction.
NCT01059604 ↗	Sumatriptan and Naratriptan Pregnancy Registry	Completed	GlaxoSmithKline		2001-12-01	Anti-migraine drugs, including triptans, are not indicated for use in pregnancy. However, the peak prevalence of migraine is in women of childbearing age. This, coupled with the sporadic nature of migraine attacks and high rates of unplanned pregnancies, makes unintentional exposure to anti-migraine medications during pregnancy likely. Prior to an anti-migraine medication being marketed there are few data available on drug safety in pregnancy: data from animal models may not translate directly to humans and pregnant women are routinely excluded from clinical trials. The Sumatriptan Pregnancy Registry was established by GlaxoSmithKline (GSK) in 1996 to monitor the safety of sumatriptan during pregnancy. It was combined with the Naratriptan Pregnancy Registry in 2001 and data collection on the sumatriptan-naproxen combination (Treximet) began in 2008.
NCT01161654 ↗	Bioequivalency Study of Naratriptan Hydrochloride 2.5 mg Under Fed Conditions	Completed	Roxane Laboratories	N/A	2007-08-01	The objective of this study was to prove the bioequivalence of Naratriptan Hydrochloride Tablet under fed conditions.

Clinical Trial Conditions for Naratriptan

Condition Name

Condition Name for Naratriptan
Intervention	Trials
Migraine	4
Migraine Disorders	3
Headache	2
Post Traumatic Headache	1

Condition MeSH

Condition MeSH for Naratriptan
Intervention	Trials
Migraine Disorders	6
Headache	3
Disruptive, Impulse Control, and Conduct Disorders	1
Post-Traumatic Headache	1

Clinical Trial Locations for Naratriptan

Trials by Country

Trials by Country for Naratriptan
Location	Trials
United States	5
Netherlands	1

Trials by US State

Trials by US State for Naratriptan
Location	Trials
Washington	2
Texas	1
North Carolina	1
Missouri	1

Clinical Trial Progress for Naratriptan

Clinical Trial Phase

Clinical Trial Phase for Naratriptan
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	2
Phase 2	1

Clinical Trial Status

Clinical Trial Status for Naratriptan
Clinical Trial Phase	Trials
Completed	5
Terminated	2
Withdrawn	2

Clinical Trial Sponsors for Naratriptan

Sponsor Name

Sponsor Name for Naratriptan
Sponsor	Trials
GlaxoSmithKline	4
Roxane Laboratories	2
Ache Laboratorios Farmaceuticos S.A.	2

Sponsor Type

Sponsor Type for Naratriptan
Sponsor	Trials
Industry	10
Other	4