CLINICAL TRIALS PROFILE FOR NOVANTRONE

All Clinical Trials for NOVANTRONE

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002003 ↗	Phase II Study of Novantrone(R) (Mitoxantrone) and Etoposide in Patients With HIV Associated Large Cell and Immunoblastic Lymphomas	Completed	Lederle Laboratories	Phase 2	1969-12-31	To determine the efficacy and toxicity of the combination of mitoxantrone hydrochloride ( Novantrone ) and etoposide in the treatment of patients with HIV associated lymphomas.
NCT00002259 ↗	Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma	Completed	Lederle Laboratories	Phase 2	1969-12-31	To study the toxicity and efficacy of IV mitoxantrone hydrochloride (Novantrone) in AIDS-related Kaposi's sarcoma.
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	National Cancer Institute (NCI)	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	Children's Oncology Group	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002835 ↗	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	National Cancer Institute (NCI)	Phase 3	1995-10-30	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
NCT00002835 ↗	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	M.D. Anderson Cancer Center	Phase 3	1995-10-30	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
NCT00006114 ↗	Combination Chemotherapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy	Unknown status	GERCOR - Multidisciplinary Oncology Cooperative Group	Phase 2	1999-05-01	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients who have metastatic prostate cancer that has not responded to hormone therapy.

Clinical Trial Conditions for NOVANTRONE

Condition Name

Condition Name for NOVANTRONE
Intervention	Trials
Recurrent Adult Acute Myeloid Leukemia	17
Acute Myeloid Leukemia	12
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities	10
Untreated Adult Acute Myeloid Leukemia	10

Condition MeSH

Condition MeSH for NOVANTRONE
Intervention	Trials
Leukemia	43
Leukemia, Myeloid, Acute	40
Leukemia, Myeloid	39
Lymphoma	13

Clinical Trial Locations for NOVANTRONE

Trials by Country

Trials by Country for NOVANTRONE
Location	Trials
United States	464
Canada	49
Australia	21
New Zealand	9
Puerto Rico	7

Trials by US State

Trials by US State for NOVANTRONE
Location	Trials
California	20
Washington	18
Texas	17
Ohio	16
New York	16

Clinical Trial Progress for NOVANTRONE

Clinical Trial Phase

Clinical Trial Phase for NOVANTRONE
Clinical Trial Phase	Trials
Phase 4	3
Phase 3	9
Phase 2	27

Clinical Trial Status

Clinical Trial Status for NOVANTRONE
Clinical Trial Phase	Trials
Completed	40
Terminated	11
Active, not recruiting	8

Clinical Trial Sponsors for NOVANTRONE

Sponsor Name

Sponsor Name for NOVANTRONE
Sponsor	Trials
National Cancer Institute (NCI)	31
Children's Oncology Group	6
Fred Hutchinson Cancer Research Center	6

Sponsor Type

Sponsor Type for NOVANTRONE
Sponsor	Trials
Other	55
Industry	31
NIH	31