This was a randomized, blinded study of transforaminal epidural injection of clonidine versus
a similar injection of corticosteroid for acute lumbosacral radiculopathy. The hypothesis was
that clonidine will be as effective as steroid for this condition.
This was a randomized, blinded study of transforaminal epidural injection of clonidine versus
a similar injection of corticosteroid for acute lumbosacral radiculopathy. The hypothesis was
that clonidine will be as effective as steroid for this condition.
A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Completed
National Center for Research Resources (NCRR)
Phase 2
2008-10-01
Fecal incontinence is the involuntary leakage of stool from the anus. Doctors at Mayo Clinic
are doing a research study to assess the effects of a medication, clonidine, on fecal
incontinence and rectal functions in women. Clonidine has been approved by the Food and Drug
Administration (FDA) for treating high blood pressure, but not for treating incontinence and
rectal functions. The hypothesis of this study is clonidine will improve fecal incontinence,
increase rectal capacity and reduce rectal sensation to a greater extent than placebo in
women.
A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Completed
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Phase 2
2008-10-01
Fecal incontinence is the involuntary leakage of stool from the anus. Doctors at Mayo Clinic
are doing a research study to assess the effects of a medication, clonidine, on fecal
incontinence and rectal functions in women. Clonidine has been approved by the Food and Drug
Administration (FDA) for treating high blood pressure, but not for treating incontinence and
rectal functions. The hypothesis of this study is clonidine will improve fecal incontinence,
increase rectal capacity and reduce rectal sensation to a greater extent than placebo in
women.
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