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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR NEPTAZANE


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All Clinical Trials for NEPTAZANE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01587027 ↗ Safety Evaluation of Aminophylline and Methazolamide Completed Defense Advanced Research Projects Agency Phase 1 2011-12-01 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01587027 ↗ Safety Evaluation of Aminophylline and Methazolamide Completed University of Colorado, Denver Phase 1 2011-12-01 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01587027 ↗ Safety Evaluation of Aminophylline and Methazolamide Completed Poudre Valley Health System Phase 1 2011-12-01 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01702025 ↗ Rapid Acclimatization to Hypoxia at Altitude Completed Defense Advanced Research Projects Agency Phase 1/Phase 2 2012-06-01 In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.
NCT01702025 ↗ Rapid Acclimatization to Hypoxia at Altitude Completed University of Colorado, Denver Phase 1/Phase 2 2012-06-01 In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.
NCT01702025 ↗ Rapid Acclimatization to Hypoxia at Altitude Completed Colorado State University Phase 1/Phase 2 2012-06-01 In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.
NCT02390284 ↗ Stop Retinal Ganglion Cell Dysfunction Study Active, not recruiting National Eye Institute (NEI) Phase 3 2015-09-01 Glaucoma is a progressive disease resulting in blindness. Determining the onset of the disease, predicting its severity and the benefit of pressure lowering eye drops is key to clinical management aimed at maintaining useful vision with advancing age. This study will longitudinally monitor a population of glaucoma suspects (with positive factors for the disease but with normal vision) with noninvasive pattern electroretinogram (PERG) and other standard eye tests for glaucoma. The PERG measures the function of retinal ganglion cells (RGCs) that are the parent neurons of the optic nerve. RGCs may become dysfunctional before dying and their function restored with pressure-lowering eye drops. Glaucoma suspects with abnormal PERG will be randomized to treatment with eye drops, while those with normal PERG will be left untreated. All patients will be monitored with PERG, Optic Coherence Tomography (OCT) and other ancillary tests every 6 months over 4 years.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for NEPTAZANE

Condition Name

Condition Name for NEPTAZANE
Intervention Trials
Glaucoma 1
Mountain Sickness 1
Physiological Function in Low Oxygen Environment 1
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Condition MeSH

Condition MeSH for NEPTAZANE
Intervention Trials
Altitude Sickness 1
Glaucoma 1
Hypoxia 1
Anoxia 1
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Clinical Trial Locations for NEPTAZANE

Trials by Country

Trials by Country for NEPTAZANE
Location Trials
United States 3
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Trials by US State

Trials by US State for NEPTAZANE
Location Trials
Colorado 2
Florida 1
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Clinical Trial Progress for NEPTAZANE

Clinical Trial Phase

Clinical Trial Phase for NEPTAZANE
Clinical Trial Phase Trials
Phase 3 1
Phase 1/Phase 2 1
Phase 1 1
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Clinical Trial Status

Clinical Trial Status for NEPTAZANE
Clinical Trial Phase Trials
Completed 2
Active, not recruiting 1
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Clinical Trial Sponsors for NEPTAZANE

Sponsor Name

Sponsor Name for NEPTAZANE
Sponsor Trials
Defense Advanced Research Projects Agency 2
University of Colorado, Denver 2
Poudre Valley Health System 1
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Sponsor Type

Sponsor Type for NEPTAZANE
Sponsor Trials
Other 5
U.S. Fed 2
NIH 1
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