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Last Updated: October 12, 2024

CLINICAL TRIALS PROFILE FOR MYLOTARG


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All Clinical Trials for Mylotarg

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00006265 ↗ Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Completed National Cancer Institute (NCI) Phase 2 2001-03-01 RATIONALE: Monoclonal antibodies, such as gemtuzumab ozogamicin, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining gemtuzumab ozogamicin with cytarabine may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining gemtuzumab ozogamicin with high-dose cytarabine in treating patients who have relapsed or refractory acute myeloid leukemia.
NCT00006265 ↗ Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia Completed Alliance for Clinical Trials in Oncology Phase 2 2001-03-01 RATIONALE: Monoclonal antibodies, such as gemtuzumab ozogamicin, can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy, such as cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining gemtuzumab ozogamicin with cytarabine may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining gemtuzumab ozogamicin with high-dose cytarabine in treating patients who have relapsed or refractory acute myeloid leukemia.
NCT00017589 ↗ Oblimersen and Gemtuzumab Ozogamicin in Treating Older Patients With Relapsed Acute Myeloid Leukemia Completed Genta Incorporated Phase 2 2000-12-01 RATIONALE: Monoclonal antibodies such as gemtuzumab ozogamicin can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Oblimersen may help gemtuzumab ozogamicin kill more cancer cells by making cancer cells more sensitive to the drug. PURPOSE: Phase II trial to study the effectiveness of combining oblimersen and gemtuzumab ozogamicin in treating older patients who have relapsed acute myeloid leukemia.
NCT00038805 ↗ Nonmyeloablative Preparative Regimen Using Mylotarg for Patients With High Risk Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myeloid Leukemia (CML) and Myelodysplastic Syndrome (MDS) Terminated Wyeth is now a wholly owned subsidiary of Pfizer Phase 2/Phase 3 2001-05-01 Primary Objective: To determine the safety and maximum tolerated dose of CMA-676 as part of an intensive but nonmyeloablative preparative regimen in older or medically infirm patients undergoing mini-allogeneic peripheral blood stem cell transplantation Secondary Objectives: 1. To evaluate response rates, engraftment kinetics and degree of chimerism achievable with this strategy. 2. To evaluate disease-free and overall survival and relapse rates. 3. To evaluate the need and ability to give multiple cycles of Mylotarg plus FA and mobilized DLI in patients not achieving complete remission.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Mylotarg

Condition Name

Condition Name for Mylotarg
Intervention Trials
Acute Myeloid Leukemia 20
Leukemia 11
Myelodysplastic Syndrome 9
Acute Myelogenous Leukemia 7
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Condition MeSH

Condition MeSH for Mylotarg
Intervention Trials
Leukemia 53
Leukemia, Myeloid, Acute 52
Leukemia, Myeloid 49
Myelodysplastic Syndromes 14
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Clinical Trial Locations for Mylotarg

Trials by Country

Trials by Country for Mylotarg
Location Trials
United States 285
Canada 24
Spain 17
Germany 6
France 6
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Trials by US State

Trials by US State for Mylotarg
Location Trials
Texas 17
New York 13
California 13
Washington 12
North Carolina 11
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Clinical Trial Progress for Mylotarg

Clinical Trial Phase

Clinical Trial Phase for Mylotarg
Clinical Trial Phase Trials
Phase 4 3
Phase 3 8
Phase 2/Phase 3 3
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Clinical Trial Status

Clinical Trial Status for Mylotarg
Clinical Trial Phase Trials
Completed 24
Recruiting 23
Active, not recruiting 4
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Clinical Trial Sponsors for Mylotarg

Sponsor Name

Sponsor Name for Mylotarg
Sponsor Trials
National Cancer Institute (NCI) 23
Pfizer 12
M.D. Anderson Cancer Center 10
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Sponsor Type

Sponsor Type for Mylotarg
Sponsor Trials
Other 67
Industry 26
NIH 23
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