A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS
Completed
Pharmacia
Phase 4
1969-12-31
To optimize Mycobacterium avium Complex (MAC) prophylaxis in AIDS patients by measuring serum
rifabutin levels and adjusting the dose accordingly. To combine rifabutin with ethambutol to
examine the effect of combination therapy in preventing or delaying the incidence of MAC
bacteremia in this patient population.
REMoxTB is a study for the "Rapid Evaluation of Moxifloxacin in the treatment of sputum smear
positive tuberculosis". REMoxTB aims to find and evaluate new drugs and regimens that shorten
the duration of tuberculosis therapy.
The purpose of REMoxTB is to evaluate the efficacy, safety and acceptability of two
moxifloxacin-containing treatment combinations to determine whether substituting ethambutol
with moxifloxacin in one combination, and/or substituting isoniazid with moxifloxacin in
another combination, makes it possible to reduce the duration of treatment for TB.
Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis
Completed
European and Developing Countries Clinical Trials Partnership (EDCTP)
Phase 3
2008-01-01
REMoxTB is a study for the "Rapid Evaluation of Moxifloxacin in the treatment of sputum smear
positive tuberculosis". REMoxTB aims to find and evaluate new drugs and regimens that shorten
the duration of tuberculosis therapy.
The purpose of REMoxTB is to evaluate the efficacy, safety and acceptability of two
moxifloxacin-containing treatment combinations to determine whether substituting ethambutol
with moxifloxacin in one combination, and/or substituting isoniazid with moxifloxacin in
another combination, makes it possible to reduce the duration of treatment for TB.
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