Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
Completed
Ionis Pharmaceuticals, Inc.
Phase 2
2006-07-01
This study will assess what, if any, effect that ISIS 301012 (mipomersen) has on liver
triglyceride content in multiple groups of subjects with varying degrees of risk for hepatic
steatosis. In order to enroll subject groups with varying degrees of risk, the study has
included multiple cohorts (Cohorts A-G). Additions and removal of cohorts has been
accomplished with protocol amendments.
Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
Completed
Kastle Therapeutics, LLC
Phase 2
2006-07-01
This study will assess what, if any, effect that ISIS 301012 (mipomersen) has on liver
triglyceride content in multiple groups of subjects with varying degrees of risk for hepatic
steatosis. In order to enroll subject groups with varying degrees of risk, the study has
included multiple cohorts (Cohorts A-G). Additions and removal of cohorts has been
accomplished with protocol amendments.
Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia
Completed
Ionis Pharmaceuticals, Inc.
Phase 2
2007-05-01
The purpose of this study is to evaluate the safety and efficacy of extended dosing of
mipomersen in patients with familial hypercholesterolemia on lipid-lowering therapy who have
completed either the 301012-CS8 (NCT00280995) or 301012-CS9 (NCT00281008) clinical drug
trials.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
