DrugPatentWatch Database Preview

CLINICAL TRIALS PROFILE FOR MEXILETINE HYDROCHLORIDE

« Back to Dashboard

Clinical Trials for Mexiletine Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00000464	Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3	To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000464	Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)	Completed	University of Washington	Phase 3	To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest.
NCT00000518	Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 3	To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000518	Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)	Completed	University of Utah	Phase 3	To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death.
NCT00000793	A Phase II/III Double-Blind Study of Amitriptyline and Mexiletine for Painful Neuropathy in HIV Infection	Completed	Boehringer Ingelheim	Phase 2	To assess the efficacy, safety, and tolerability of amitriptyline hydrochloride versus mexiletine hydrochloride in reducing pain intensity in patients with HIV-related painful peripheral neuropathy. No large-scale controlled clinical trials of symptomatic therapy for painful HIV-related neuropathy have been attempted. Both amitriptyline and mexiletine have been useful in the management of painful neuropathies; however, both are associated with certain toxicities. In this comparative study of amitriptyline and mexiletine, benztropine mesylate also will be included as an active placebo to mimic the side effects of the study drugs.

Clinical Trial Conditions for Mexiletine Hydrochloride

Condition Name

Condition Name for Mexiletine Hydrochloride
Intervention	Trials
Myotonia Congenita	2
Paramyotonia Congenita	2
Ventricular Fibrillation	2
Cardiovascular Diseases	2

Export unavailable in trial.
Subscribe for complete access.

Condition MeSH

Condition MeSH for Mexiletine Hydrochloride
Intervention	Trials
Myotonia	4
Motor Neuron Disease	3
Amyotrophic Lateral Sclerosis	3
Sclerosis	3

Export unavailable in trial.
Subscribe for complete access.

Clinical Trial Locations for Mexiletine Hydrochloride

Trials by Country

Trials by Country for Mexiletine Hydrochloride
Location	Trials
United States	70
Canada	4
Netherlands	2
United Kingdom	2
Denmark	2

Export unavailable in trial.
Subscribe for complete access.

Trials by US State

Trials by US State for Mexiletine Hydrochloride
Location	Trials
New York	7
Massachusetts	5
California	5
Pennsylvania	4
Missouri	3

Export unavailable in trial.
Subscribe for complete access.

Clinical Trial Progress for Mexiletine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Mexiletine Hydrochloride
Clinical Trial Phase	Trials
Phase 4	4
Phase 3	5
Phase 2/Phase 3	2

Export unavailable in trial.
Subscribe for complete access.

Clinical Trial Status

Clinical Trial Status for Mexiletine Hydrochloride
Clinical Trial Phase	Trials
Completed	17
Recruiting	4
Active, not recruiting	2

Export unavailable in trial.
Subscribe for complete access.

Clinical Trial Sponsors for Mexiletine Hydrochloride

Sponsor Name

Sponsor Name for Mexiletine Hydrochloride
Sponsor	Trials
University of Washington	3
University of Rochester	2
National Heart, Lung, and Blood Institute (NHLBI)	2

Export unavailable in trial.
Subscribe for complete access.

Sponsor Type

Sponsor Type for Mexiletine Hydrochloride
Sponsor	Trials
Other	25
NIH	6
U.S. Fed	2

Export unavailable in trial.
Subscribe for complete access.