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CLINICAL TRIALS PROFILE FOR METHAZOLAMIDE

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Clinical Trials for Methazolamide

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00257829	Improving Tumor Oxygenation in Cervical Cancer	Withdrawn	University of California, Irvine	Phase 2	The Phenomenon of Tumor Hypoxia Many solid tumors are relatively resistant to treatment with ionizing radiation and certain chemotherapeutic agents such as anthracyclines that are affected adversely by acidic pH. These effects have primarily been attributed to the presence of hypoxic cells within the tumor. The relevance of hypoxia with respect to failure of radiotherapy to cure certain malignancies has had a chequered history. However, in recent years the evidence that hypoxia plays a central role in relative radioresistance has become more compelling. Since approximately two-thirds of all women suffering from cervical carcinoma receive radiation as a component of their therapy, an enhanced understanding of the interactions between hypoxia and radiation as a component of their therapy, an enhanced understanding of the interactions between hypoxia and radiation resistance is critical to improving outcome among those with cervical cancer.
NCT01587027	Safety Evaluation of Aminophylline and Methazolamide	Completed	Defense Advanced Research Projects Agency	Phase 1	This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01587027	Safety Evaluation of Aminophylline and Methazolamide	Completed	University of Colorado, Denver	Phase 1	This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.

Clinical Trial Conditions for Methazolamide

Condition Name

Condition Name for Methazolamide
Intervention	Trials
Mountain Sickness	2
Physiological Function in Low Oxygen Environment	1
Hypoxia	1

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Condition MeSH

Condition MeSH for Methazolamide
Intervention	Trials
Altitude Sickness	3
Hypertension, Pulmonary	1
Fatigue	1

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Clinical Trial Locations for Methazolamide

Trials by Country

Trials by Country for Methazolamide
Location	Trials
United States	3
Canada	2

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Trials by US State

Trials by US State for Methazolamide
Location	Trials
Colorado	2
Michigan	1

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Clinical Trial Progress for Methazolamide

Clinical Trial Phase

Clinical Trial Phase for Methazolamide
Clinical Trial Phase	Trials
Phase 4	3
Phase 2	1
Phase 1/Phase 2	1

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Clinical Trial Status

Clinical Trial Status for Methazolamide
Clinical Trial Phase	Trials
Completed	3
Recruiting	2
Withdrawn	1

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Clinical Trial Sponsors for Methazolamide

Sponsor Name

Sponsor Name for Methazolamide
Sponsor	Trials
University of Colorado, Denver	3
University of British Columbia	2
Defense Advanced Research Projects Agency	2

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Sponsor Type

Sponsor Type for Methazolamide
Sponsor	Trials
Other	9
U.S. Fed	2

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