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Generated: December 10, 2018

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CLINICAL TRIALS PROFILE FOR METHAZOLAMIDE

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Clinical Trials for Methazolamide

Trial ID Title Status Sponsor Phase Summary
NCT00257829 Improving Tumor Oxygenation in Cervical Cancer Withdrawn University of California, Irvine Phase 2 The Phenomenon of Tumor Hypoxia Many solid tumors are relatively resistant to treatment with ionizing radiation and certain chemotherapeutic agents such as anthracyclines that are affected adversely by acidic pH. These effects have primarily been attributed to the presence of hypoxic cells within the tumor. The relevance of hypoxia with respect to failure of radiotherapy to cure certain malignancies has had a chequered history. However, in recent years the evidence that hypoxia plays a central role in relative radioresistance has become more compelling. Since approximately two-thirds of all women suffering from cervical carcinoma receive radiation as a component of their therapy, an enhanced understanding of the interactions between hypoxia and radiation as a component of their therapy, an enhanced understanding of the interactions between hypoxia and radiation resistance is critical to improving outcome among those with cervical cancer.
NCT01587027 Safety Evaluation of Aminophylline and Methazolamide Completed Defense Advanced Research Projects Agency Phase 1 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01587027 Safety Evaluation of Aminophylline and Methazolamide Completed University of Colorado, Denver Phase 1 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01587027 Safety Evaluation of Aminophylline and Methazolamide Completed Poudre Valley Health System Phase 1 This safety study is the first in a series of studies testing the application of the combination of aminophylline and methazolamide.
NCT01702025 Rapid Acclimatization to Hypoxia at Altitude Completed Defense Advanced Research Projects Agency Phase 1/Phase 2 In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Methazolamide

Condition Name

Condition Name for Methazolamide
Intervention Trials
Mountain Sickness 2
Altitude Sickness 1
Physiological Function in Low Oxygen Environment 1
Hypoxia 1
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Condition MeSH

Condition MeSH for Methazolamide
Intervention Trials
Altitude Sickness 3
Hypertension, Pulmonary 1
Fatigue 1
Anoxia 1
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Clinical Trial Locations for Methazolamide

Trials by Country

Trials by Country for Methazolamide
Location Trials
United States 3
Canada 2
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Trials by US State

Trials by US State for Methazolamide
Location Trials
Colorado 2
Michigan 1
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Clinical Trial Progress for Methazolamide

Clinical Trial Phase

Clinical Trial Phase for Methazolamide
Clinical Trial Phase Trials
Phase 4 3
Phase 2 1
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for Methazolamide
Clinical Trial Phase Trials
Completed 3
Recruiting 2
Withdrawn 1
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Clinical Trial Sponsors for Methazolamide

Sponsor Name

Sponsor Name for Methazolamide
Sponsor Trials
University of Colorado, Denver 3
Defense Advanced Research Projects Agency 2
University of British Columbia 2
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Sponsor Type

Sponsor Type for Methazolamide
Sponsor Trials
Other 9
U.S. Fed 2
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