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Last Updated: January 27, 2023

CLINICAL TRIALS PROFILE FOR METHADOSE


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All Clinical Trials for Methadose

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00149630 ↗ Pharmacogenetics of Disulfiram for Cocaine Completed National Institute on Drug Abuse (NIDA) Phase 2 2005-01-01 Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH.
NCT00149630 ↗ Pharmacogenetics of Disulfiram for Cocaine Completed Yale University Phase 2 2005-01-01 Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH.
NCT00149630 ↗ Pharmacogenetics of Disulfiram for Cocaine Completed Baylor College of Medicine Phase 2 2005-01-01 Previous research has shown that disulfiram, a medication sometimes used for treating alcoholism, discourages cocaine use among cocaine addicts who are undergoing methadone treatment. By blocking the enzyme dopamine beta hydroxylase (DBH), disulfiram increases levels of dopamine and produces an unpleasant sense of hyperstimulation and discomfort in cocaine users. This study will evaluate the effectiveness of disulfiram in preventing drug relapse among cocaine and opiate addicts with varying inherited levels of DBH.
NCT00573937 ↗ Methadone Versus Morphine for Cancer-Related Pain Terminated Mayo Clinic Phase 2 2007-08-01 The purpose of this study is to compare methadone with morphine in the management of moderate to severe cancer pain.
NCT00726830 ↗ Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer Terminated National Cancer Institute (NCI) N/A 2009-03-01 RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer. PURPOSE: This randomized clinical trial is studying methadone to see how well it works compared with morphine or oxycodone in treating pain in patients with cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Methadose

Condition Name

Condition Name for Methadose
Intervention Trials
Pain 3
Cancer Pain 1
Neoplasms 1
Chronic Myeloproliferative Disorders 1
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Condition MeSH

Condition MeSH for Methadose
Intervention Trials
Cancer Pain 2
Opioid-Related Disorders 2
Lymphoproliferative Disorders 1
Neoplasms, Plasma Cell 1
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Clinical Trial Locations for Methadose

Trials by Country

Trials by Country for Methadose
Location Trials
United States 6
Canada 4
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Trials by US State

Trials by US State for Methadose
Location Trials
Texas 2
Kentucky 1
South Carolina 1
Arizona 1
New York 1
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Clinical Trial Progress for Methadose

Clinical Trial Phase

Clinical Trial Phase for Methadose
Clinical Trial Phase Trials
Phase 4 2
Phase 3 1
Phase 2 2
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Clinical Trial Status

Clinical Trial Status for Methadose
Clinical Trial Phase Trials
Completed 4
Terminated 2
Not yet recruiting 1
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Clinical Trial Sponsors for Methadose

Sponsor Name

Sponsor Name for Methadose
Sponsor Trials
National Cancer Institute (NCI) 2
Bruyere Research Institute 1
National Institute on Drug Abuse (NIDA) 1
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Sponsor Type

Sponsor Type for Methadose
Sponsor Trials
Other 11
NIH 3
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