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Chubb
US Department of Justice
Baxter
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Fuji
Citi
Accenture
Federal Trade Commission
Mallinckrodt

Generated: December 18, 2018

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CLINICAL TRIALS PROFILE FOR MEKINIST

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Clinical Trials for Mekinist

Trial ID Title Status Sponsor Phase Summary
NCT01438554 Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Active, not recruiting GlaxoSmithKline Phase 1 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Active, not recruiting National Comprehensive Cancer Network Phase 1 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Active, not recruiting Sidney Kimmel Comprehensive Cancer Center Phase 1 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01553851 GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer Completed National Comprehensive Cancer Network Phase 2 This phase II trial studies how trametinib effects tumor cells in patients with oral cavity squamous cell carcinoma that can be removed by surgery. Trametinib may shrink the tumor by blocking an enzyme pathway needed for cell growth.
NCT01553851 GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer Completed Washington University School of Medicine Phase 2 This phase II trial studies how trametinib effects tumor cells in patients with oral cavity squamous cell carcinoma that can be removed by surgery. Trametinib may shrink the tumor by blocking an enzyme pathway needed for cell growth.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Mekinist

Condition Name

Condition Name for Mekinist
Intervention Trials
Melanoma 12
Recurrent Melanoma 6
Stage IV Skin Melanoma 6
Stage IIIC Skin Melanoma 6
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Condition MeSH

Condition MeSH for Mekinist
Intervention Trials
Melanoma 22
Carcinoma 9
Carcinoma, Non-Small-Cell Lung 7
Lung Neoplasms 7
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Clinical Trial Locations for Mekinist

Trials by Country

Trials by Country for Mekinist
Location Trials
United States 335
Canada 7
United Kingdom 6
Germany 5
Netherlands 2
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Trials by US State

Trials by US State for Mekinist
Location Trials
California 14
Texas 14
Massachusetts 14
Ohio 13
New York 13
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Clinical Trial Progress for Mekinist

Clinical Trial Phase

Clinical Trial Phase for Mekinist
Clinical Trial Phase Trials
Phase 3 1
Phase 2/Phase 3 1
Phase 2 27
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Clinical Trial Status

Clinical Trial Status for Mekinist
Clinical Trial Phase Trials
Recruiting 34
Not yet recruiting 11
Active, not recruiting 6
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Clinical Trial Sponsors for Mekinist

Sponsor Name

Sponsor Name for Mekinist
Sponsor Trials
National Cancer Institute (NCI) 27
Novartis 7
Novartis Pharmaceuticals 6
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Sponsor Type

Sponsor Type for Mekinist
Sponsor Trials
Other 47
Industry 31
NIH 27
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Serving hundreds of leading biopharmaceutical companies globally:

Medtronic
Cipla
Daiichi Sankyo
US Army
Fish and Richardson
Argus Health
Chinese Patent Office
Harvard Business School
Queensland Health

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