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CLINICAL TRIALS PROFILE FOR MEKINIST

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Clinical Trials for Mekinist

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01438554	Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma	Active, not recruiting	GlaxoSmithKline	Phase 1	The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554	Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma	Active, not recruiting	National Comprehensive Cancer Network	Phase 1	The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554	Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma	Active, not recruiting	Sidney Kimmel Comprehensive Cancer Center	Phase 1	The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.

Clinical Trial Conditions for Mekinist

Condition Name

Condition Name for Mekinist
Intervention	Trials
Melanoma	12
Stage IV Skin Melanoma	6
Recurrent Melanoma	6

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Condition MeSH

Condition MeSH for Mekinist
Intervention	Trials
Melanoma	22
Carcinoma	10
Lung Neoplasms	7

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Clinical Trial Locations for Mekinist

Trials by Country

Trials by Country for Mekinist
Location	Trials
United States	335
Canada	7
United Kingdom	6
Germany	5
France	3

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Trials by US State

Trials by US State for Mekinist
Location	Trials
Texas	14
Massachusetts	14
California	14
New York	13
Ohio	13

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Clinical Trial Progress for Mekinist

Clinical Trial Phase

Clinical Trial Phase for Mekinist
Clinical Trial Phase	Trials
Phase 3	2
Phase 2/Phase 3	1
Phase 2	27

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Clinical Trial Status

Clinical Trial Status for Mekinist
Clinical Trial Phase	Trials
Recruiting	35
Not yet recruiting	12
Active, not recruiting	6

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Clinical Trial Sponsors for Mekinist

Sponsor Name

Sponsor Name for Mekinist
Sponsor	Trials
National Cancer Institute (NCI)	27
Novartis	7
Novartis Pharmaceuticals	7

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Sponsor Type

Sponsor Type for Mekinist
Sponsor	Trials
Other	54
Industry	32
NIH	27

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