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Last Updated: December 11, 2024

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CLINICAL TRIALS PROFILE FOR MEKINIST


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All Clinical Trials for Mekinist

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01438554 ↗ Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Completed GlaxoSmithKline Phase 1 2011-10-01 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 ↗ Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Completed National Comprehensive Cancer Network Phase 1 2011-10-01 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 ↗ Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Completed Novartis Phase 1 2011-10-01 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 ↗ Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Completed Sidney Kimmel Comprehensive Cancer Center Phase 1 2011-10-01 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01438554 ↗ Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma Completed Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Phase 1 2011-10-01 The purpose of this study is to determine the safety and toxicity of the combination of pazopanib and GSK1120212 in patients with solid tumors and identify the maximum tolerated dose (MTD) of this combination for phase II study.
NCT01553851 ↗ GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer Completed National Comprehensive Cancer Network Phase 2 2013-02-01 This phase II trial studies how trametinib effects tumor cells in patients with oral cavity squamous cell carcinoma that can be removed by surgery. Trametinib may shrink the tumor by blocking an enzyme pathway needed for cell growth.
NCT01553851 ↗ GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer Completed Washington University School of Medicine Phase 2 2013-02-01 This phase II trial studies how trametinib effects tumor cells in patients with oral cavity squamous cell carcinoma that can be removed by surgery. Trametinib may shrink the tumor by blocking an enzyme pathway needed for cell growth.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Mekinist

Condition Name

Condition Name for Mekinist
Intervention Trials
Melanoma 14
Advanced Malignant Solid Neoplasm 8
Recurrent Melanoma 7
Refractory Malignant Solid Neoplasm 7
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Condition MeSH

Condition MeSH for Mekinist
Intervention Trials
Melanoma 27
Neoplasms 16
Carcinoma 16
Carcinoma, Non-Small-Cell Lung 11
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Clinical Trial Locations for Mekinist

Trials by Country

Trials by Country for Mekinist
Location Trials
United States 533
Canada 18
United Kingdom 12
Australia 11
France 7
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Trials by US State

Trials by US State for Mekinist
Location Trials
Texas 30
California 25
Massachusetts 22
Pennsylvania 21
Ohio 20
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Clinical Trial Progress for Mekinist

Clinical Trial Phase

Clinical Trial Phase for Mekinist
Clinical Trial Phase Trials
Phase 4 1
Phase 3 2
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for Mekinist
Clinical Trial Phase Trials
Recruiting 35
Active, not recruiting 30
Completed 11
[disabled in preview] 16
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Clinical Trial Sponsors for Mekinist

Sponsor Name

Sponsor Name for Mekinist
Sponsor Trials
National Cancer Institute (NCI) 42
Novartis 15
Novartis Pharmaceuticals 12
[disabled in preview] 21
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Sponsor Type

Sponsor Type for Mekinist
Sponsor Trials
Other 103
Industry 68
NIH 42
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