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CLINICAL TRIALS PROFILE FOR MECAMYLAMINE HYDROCHLORIDE

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Clinical Trials for Mecamylamine Hydrochloride

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00006399	Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease	Completed	Alzheimer's Association	Phase 2	The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.
NCT00006399	Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease	Completed	Eisai Inc.	Phase 2	The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.
NCT00006399	Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease	Completed	Pfizer	Phase 2	The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.
NCT00006399	Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease	Completed	National Center for Research Resources (NCRR)	Phase 2	The goal of this study is to examine whether the administration of estrogen to post-menopausal women and women with mild to moderate Alzheimer's disease will enhance their memory and their capacity for learning.
NCT00018161	Treatment to Quit Smoking	Completed	VA Office of Research and Development	Phase 2	This protocol evaluates the efficacy of combining pharmacologic treatments for smoking cessation, entailing the use of the nicotine skin patch with the nicotinic antagonist mecamylamine, with a specific behavioral therapy designed to inhibit the smoking urge.
NCT00018187	Combinations of Pharmacologic Smoking Cessation Treatments	Completed	VA Office of Research and Development	Phase 1	The purpose of this study is to test the effectiveness of a combination of the drugs bupropion and mecamylamine along with a nicotine patch as a therapy for smoking cessation.

Clinical Trial Conditions for Mecamylamine Hydrochloride

Condition Name

Condition Name for Mecamylamine Hydrochloride
Intervention	Trials
Major Depressive Disorder	8
Depression	6
Smoking	2
Healthy	2

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Condition MeSH

Condition MeSH for Mecamylamine Hydrochloride
Intervention	Trials
Depressive Disorder	10
Depression	10
Depressive Disorder, Major	9
Disease	8

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Clinical Trial Locations for Mecamylamine Hydrochloride

Trials by Country

Trials by Country for Mecamylamine Hydrochloride
Location	Trials
United States	113
India	42
Japan	11
Germany	4
Colombia	4

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Trials by US State

Trials by US State for Mecamylamine Hydrochloride
Location	Trials
Ohio	7
Kansas	6
Florida	6
Connecticut	6
California	6

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Clinical Trial Progress for Mecamylamine Hydrochloride

Clinical Trial Phase

Clinical Trial Phase for Mecamylamine Hydrochloride
Clinical Trial Phase	Trials
Phase 3	7
Phase 2	11
Phase 1/Phase 2	1

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Clinical Trial Status

Clinical Trial Status for Mecamylamine Hydrochloride
Clinical Trial Phase	Trials
Completed	24
Terminated	2
Active, not recruiting	1

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Clinical Trial Sponsors for Mecamylamine Hydrochloride

Sponsor Name

Sponsor Name for Mecamylamine Hydrochloride
Sponsor	Trials
AstraZeneca	10
Targacept Inc.	7
Yale University	3

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Sponsor Type

Sponsor Type for Mecamylamine Hydrochloride
Sponsor	Trials
Industry	23
Other	17
NIH	3

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